摘要
近年来,基于碳点与适配体构建的荧光生物传感器引起了人们强烈的兴趣。与传统荧光染料、半导体量子点及稀土荧光材料相比,以碳点为荧光基元的生物传感器荧光稳定性更好,毒性更低,价格更便宜,在环境监测、生物成像及生物医疗方面有着广泛的应用前景。本文对基于碳点与适配体构建的荧光生物传感器发展现状进行了系统的总结,包括碳点与适配体介绍,近年来基于碳点与适配体的荧光生物传感器的构建方式、传感机理以及应用范围,最后对基于碳点与适配体构建的荧光生物传感器的发展方向进行了展望。
Recently,the fluorescence biosensor based on carbon dots(CDs)and aptamer is more and more attractive.Comparing with traditional fluorescence materials like fluorescence dye,semiconductor quantum dots and rare earth phosphors,CDs have attracted considerable attention in the field of fluorescence biosensor due to their excellent photoluminescence,low toxicity and low-cost prepare process.The fluorescence biosensor based on CDs and aptamer has extensive application prospect in the field of environment monitoring,bioimaging and biomedicine.This review will summarize the structural composition,fabrication methods,sensing mechanism and application area of fluorescence biosensor based on CDs and aptamer.
作者
朱志承
杨柏
ZHU Zhi-cheng;YANG Bai(State Key Laboratory of Supramolecular Structure and Materials, College of Chemistry, Jilin University, Changchun 130012, China)
出处
《发光学报》
EI
CAS
CSCD
北大核心
2021年第8期1196-1214,共19页
Chinese Journal of Luminescence
基金
国家自然科学基金(22035001)资助项目。
关键词
碳点
适配体
荧光生物传感器
传感机理
carbon dots
aptamer
fluorescence biosensor
sensing mechanism
