摘要
目的评估多普勒超声和剪切波弹性成像技术在移植肾急性肾损伤(AKI)中的应用价值。方法收集患者的一般人口学、超声影像学以及血液检查资料,采用t检验、χ2检验及Logistic回归分析等统计方法评估多普勒超声和剪切波弹性成像技术在移植肾AKI中的应用价值。结果共有202例纳入研究,67例发生AKI,发生率为33.17%。单因素分析发现移植肾AKI人群年龄较大(t=2.87,P<0.01),移植肾长径较短(t=2.56,P=0.01),不同动脉的峰值流速均较小(P<0.01),阻力指数和搏动指数较高(P<0.01),肾皮质弹性最大值、均值和最小值均较高(t=4.21,P<0.01;t=4.92,P<0.01;t=4.34,P<0.01);Logistic回归分析发现移植肾长径[OR=0.96,95%CI(0.90~0.99)]和肾主动脉峰值流速[OR=0.98,95%CI(0.97~0.99)]是肾移植术后AKI的保护因素。结论多普勒超声技术在评估肾移植术后AKI发生有着一定的应用前景,弹性成像技术能否用于肾移植术后AKI的评估有待进一步研究。
Objective To evaluate the value of color doppler ultrasonography and shear wave elastography in the acute kidney injury after the kidney transplantation.Methods The data of general demographic,ultrasound and blood index had been collected.t test,χ2 test and logistic regression model had been used to analyze the data.Results 202 patients were included in this survey,and 67 patients were AKI.Univariate analysis found that AKI after the kidney transplantation had an older age(t=2.87,P<0.01),shorter length of transplanted kidney(t=2.56,P=0.01),lower peak systolic velocity(P<0.01),higher resistance index and pulsatility index(P<0.01),higher scores of max,mean and min values of renal cortex(t=4.21,P<0.01;t=4.92,P<0.01;t=4.34,P<0.01).Logistic regression model analysis found that length of transplanted kidney(OR=0.96,[95%CI,0.90-0.99])and PSV of renal aorta(OR=0.98,[95%CI,0.97-0.99])were protective factors.Conclusion The technique of doppler ultrasonography has a certain application prospect in evaluating the occurrence of AKI after kidney transplantation,while the technique of shear wave elastography needs further study.
作者
陈霞
付文学
赵宸
陈姣姣
房静
何年安
Chen Xia;Fu Wenxue;Zhao Chen(Dept of Ultrasound,The First Affiliated Hospital,University of Science and Technology of China,Hefei 230001;Dept of Nephrology,The First Affiliated Hospital,University of Science and Technology of China,Hefei 230001)
出处
《安徽医科大学学报》
CAS
北大核心
2021年第9期1492-1495,共4页
Acta Universitatis Medicinalis Anhui
基金
国家自然科学基金(编号:81271594)
安徽省自然科学基金(编号:1608085MH235、1808085QH246)。
关键词
多普勒超声
剪切波弹性成像
移植肾
急性肾损伤
doppler ultrasonography
shear wave elastography
kidney transplantation
acute kidney injury
