摘要
目的建立工作场所空气中15种蒸气态有机酸的溶剂解吸-气相色谱同时测定方法。方法以硅胶管采集工作场所空气中蒸气态的乙酸、丙酸、丁酸、戊酸等15种有机酸,用丙酮解吸,经硝基对苯二甲酸改性的聚乙二醇毛细管色谱柱分离,火焰离子化检测器检测。结果15种有机酸在选定的定量范围内线性关系良好,相关系数在0.99997~0.99998。方法的检出限为0.04~0.29 mg/L,最低检出浓度范围为0.03~0.19 mg/m3(以采集1.50 L空气计算)。方法的平均解吸效率为92.9%~98.5%,批内相对标准偏差(RSD)和批间RSD分别为0.3%~1.6%和1.5%~3.0%,样品在室温下至少可以保存15 d。结论本方法操作简单,灵敏度高,精密度好,适用于工作场所和应急事故现场空气中15种蒸气态有机酸的同时测定。
Objective To establish a method for simultaneous determination of 15 kinds of vapor state organic acids in workplace air by solvent desorption-gas chromatography.Methods A total 15 kinds of vapor state organic acids such as acetic acid,propanoic acid,butyric acid and pentanoic acid in the air of workplace were collected by silica gel,eluted with acetone,separated by DB-FFAP capillary chromatograph column,and detected by gas chromatography with flame ionization detection.Results There was a good linear relationship in the selected range of 15 kinds of organic acids.The coefficient correlation was 0.99997-0.99998.The limit of detection of this method was 0.04-0.29 mg/L,and the minimum detection concentration was 0.03-0.19 mg/m3(collected sample volume was 1.50 L).The average desorption efficiency was 92.9%-98.5%.The withinrun and between-run relative standard deviation was 0.3%-1.6%and 1.5%-3.0%,respectively.The samples could be kept for at least 15 days at room temperature.Conclusion The method is simple for operation,with high sensitivity,and good precision,which is suitable for simultaneous determination of 15 kinds of vapor state organic acids in the air of workplace and sites of emergency accident.
作者
陈冠林
陈馥
骆春霞
韩门娣
谭强
梁俭仪
周雪琼
陈松根
CHEN Guan-lin;CHEN Fu;LUO Chun-xia;HAN Men-di;TAN Qiang;LIANG Jian-yi;ZHOU Xue-qiong;CHEN Song-gen(Foshan Institute of Occupational Disease Prevention and Control,Foshan,Guangdong 528000,China;不详)
出处
《中国职业医学》
CAS
北大核心
2021年第2期182-187,共6页
China Occupational Medicine
基金
广东省医学科学技术研究基金(A2015617,A2018340,B2021212)
佛山市医学类科技攻关项目(1920001000268)
佛山市医学科学技术研究项目(20200399)
南方医科大学科学技术研究启动计划项目(QD2018N007)。
关键词
工作场所
空气
酸
气相色谱
溶剂解吸
Workplace
Air
Acid
Gas chromatography
Solvent desorption
