摘要
镁及镁合金具有与骨骼硬组织良好的力学性能适配性、生物相容性和体内可生物降解等优良特性,被认为是一种最具有应用潜力的新型外科金属基植入材料,但其过快的降解速度限制了它的应用和普及推广。羟基磷灰石(HA)具有良好的生物活性,在镁合金表面制备HA涂层,能有效增强镁合金植入体的活性和耐腐蚀性,延缓其降解速率。但纯的HA涂层存在脆性大,强韧性不足,与基体间黏附力较差且功能性单一等问题,因此开发镁合金表面的高品质、多功能HA复合涂层,具有非常重要的科学和实践价值。本文综述了近年来开发的在镁合金基体表面的HA复合涂层及在骨修复上应用的研究进展,并对未来镁合金基体表面HA复合涂层的研究发展趋势进行了展望。
On account of their excellent adaptability of mechanical properties with hard tissue bone, biocompatibility and biodegradability, magnesium and its alloys are considered as a new type of surgical metal-based implant material with the most potential application, however, their rapid degradation rate limits their application and popularization. Hydroxyapatite(HA) has an excellent bioactivity, it can enhance the corrosion resistance and bioactivity of magnesium alloys, and decrease the degradation of magnesium alloys when it is fabricated as a coating on magnesium alloys. Nevertheless, pure HA coating still exists some problems of brittleness, insufficient toughness and poor adhesion between coating and magnesium alloy surface, therefore, to explore a HA composite coating on magnesium alloys is of great scientific and practical value. This paper reviewed the development of HA composite coating on magnesium alloy and its application in bone repair in recent years, and forecasted the development trend of HA composite coating on magnesium alloys.
作者
符青云
李卫
余森
于振涛
Fu Qingyun;Li Wei;Yu Sen;Yu Zhentao(Institute of Advanced Wear&Corrosion Resistant and Functional Materials,Jinan University,Guangzhou 510632,China;Northwest Institute for Nonferrous Metal Research,Xi’an 710016,China)
出处
《稀有金属材料与工程》
SCIE
EI
CAS
CSCD
北大核心
2021年第7期2630-2640,共11页
Rare Metal Materials and Engineering
基金
陕西省重点研发计划(2019ZDLSF03-06)。
关键词
镁合金
羟基磷灰石
复合涂层
骨修复
magnesium alloy
hydroxyapatite
compostite coating
bone repair
