摘要
帕金森病是一种常见的神经系统退行性疾病,但是由于缺少可信度高的生物标志物,导致其临床诊断极具挑战性。分子影像技术是将分子生物学技术和现代医学影像学结合的一门新兴技术。近年来,分子影像技术在帕金森病的诊断和鉴别诊断中的作用也得到了越来越多的证据支持,能为帕金森病的早期诊断和鉴别诊断提供重要依据。虽然关于分子影像在帕金森病的诊断和鉴别诊断中的研究结果日渐增多,但其临床应用仍不充分。因此,很有必要认识分子影像技术的研究现状,以及探讨未来的发展方向,以期更合理地利用这项技术,更好地服务于临床。
Parkinson′s disease(PD)is a common neurodegenerative disease,but due to the lack of reliable biomarkers,the clinical diagnosis of PD is challenging.Molecular imaging technology is a new technology which combines molecular biology technology with modern medical imaging.In recent years,the role of molecular imaging technology in the diagnosis and differential diagnosis of PD has been supported by more and more evidences,which can provide an important basis for the early diagnosis and differential diagnosis of PD.Although the research results of molecular imaging in the diagnosis and differential diagnosis of PD are increasing,the clinical application is still insufficient.Therefore,it is necessary to understand the research status of molecular imaging technology,and explore the future development direction,in order to make more rational use of this technology and better serve the clinical practice.
作者
吴佳薇
兰晓莉
王涛
Wu Jiawei;Lan Xiaoli;Wang Tao(Department of Neurology,Union Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430022,China)
出处
《中华神经科杂志》
CAS
CSCD
北大核心
2021年第8期751-757,共7页
Chinese Journal of Neurology
基金
国家自然科学基金(81974201,81671260)
国家重点研发计划(2016YFC1306000,2017YFC1310200)。
