摘要
目的分析超广角荧光素眼底血管造影(UWFA)下眼底正常眼周边视网膜的荧光特征。方法采用横断面研究方法,纳入2016年7月至2019年1月于武汉大学人民医院行常规UWFA检查的受试者95例190眼,其中男94眼,占49.47%,女96眼,占50.53%;轻微白内障72眼,占37.89%,中低度近视60眼,占31.58%,主观性视物困扰58眼,占30.53%。根据UWFA检查周围视网膜荧光特征是否涉及视网膜血管将其分为血管相关特征和非血管相关特征2类。根据年龄将受试者分为≤40岁组和>40岁组,比较2个组各种特征的差异。结果周边视网膜荧光非血管特征包括均匀高荧光158眼,高低荧光混杂边界82眼,椒盐状高荧光24眼,局部斑驳高荧光21眼,分别占83.16%、43.16%、12.63%和11.05%。周边视网膜荧光血管相关特征包括周边无血管区92眼,血管跨过锯齿缘66眼,微血管瘤60眼,晚期荧光素轻微渗漏56眼,微血管扩张30眼,分别占48.42%、34.74%、31.58%、29.47%和15.79%。>40岁组周边视网膜血管跨过锯齿缘眼数百分比为19.61%(20/102),明显低于≤40岁组的52.27%(46/88),微血管瘤及微血管扩张眼数百分比分别为43.10%(44/102)和19.61%(20/102),明显高于≤40岁组的18.23%(16/88)和11.36%(10/88),差异均有统计学意义(χ^(2)=22.235、10.451、9.259,均P<0.01)。结论UWFA揭示眼底正常眼周边部视网膜4个非血管荧光特征和5个血管荧光特征。年龄可能对周边视网膜血管跨过锯齿缘、微血管瘤及微血管扩张荧光特征产生影响。
Objective To analyze the peripheral retinal fluorescence characteristics of normal fundus on ultra-wide field fluorescein angiography(UWFA)images.Methods A cross-sectional study was conducted.Ninety-five patients(190 eyes)who underwent normal UWFA in Renmin Hospital of Wuhan University from July 2016 to January 2019 were enrolled.There were 94(49.47%)male eyes and 96(50.53%)female eyes.Among them,there were 72(37.89%)mild cataract eyes,60(31.58%)moderate and low myopia eyes and 58(30.53%)subjective blurred vision eyes.The peripheral retinal fluorescence characteristics were divided into vascular-associated feature or non-vascular feature according to whether the retinal vessel involved or not.The subjects were divided into≤40 years old group and>40 years old group,and the differences in various features between the two groups were compared and analyzed.The study protocol adhered to the Declaration of Helsinki and was approved by an Ethics Committee of Renmin Hospital of Wuhan University(No.WDRY2019-K037).Written informed consent was obtained from each patient prior to any examination.Results Four non-vascular and five vascular-associated fluorescence features were found in normal peripheral retina.Non-vascular features contained glass hyperfluorescence in 158(83.16%)eyes,far peripheral retina with mottled florescent band in 82(43.16%)eyes,granular ground hyperfluorescence in 24(12.63%)eyes and local mottled fluorescence in 21(11.05%)eyes.Vascular-associated fluorescence features included peripheral avascular area in 92(48.42%)eyes,vessels passing through the ora serrata in 66(34.74%)eyes,microaneurysm in 60(31.58%)eyes,slight leakage within 10 minutes after angiography in 56(29.47%)eyes and angiotelectasis in 30(15.79%)eyes.There were 19.61%(20/102)of eyes with peripheral retinal vessels passing through the ora serrata and 43.10%(44/102)of eyes with microaneurysm and 19.61%(20/102)of eyes with angiotelectasis in>40 years old group,and there were 52.27%(46/88),18.23%(16/88)and 11.36%(10/88)correspondingly in≤4
作者
王晓玲
陈长征
许阿敏
易佐慧子
何璐
刘珏君
郑红梅
Wang Xiaoling;Chen Changzheng;Xu Amin;Yi Zuohuizi;He Lu;Liu Juejun;Zheng Hongmei(Department of Ophthalmology,Renmin Hospital of Wuhan University,Wuhan 430060,China)
出处
《中华实验眼科杂志》
CAS
CSCD
北大核心
2021年第7期609-613,共5页
Chinese Journal Of Experimental Ophthalmology
关键词
正常眼/诊断
荧光素血管造影术
诊断技术
眼科
Normal eye/diagnosis
Fluorescein angiography
Diagnostic technique,ophthalmology
