摘要
目的比较乳腺托架、乳腺托架联合U膜、真空垫联合翼型板3种不同的体位固定方式在乳腺癌调强放射治疗中的摆位误差,以找到更好的个体化固定方式。方法选择2019年6月至2020年5月接受放射治疗的女性乳腺癌患者60例,年龄32~65岁,中位年龄45岁。随机分成A、B、C 3组,每组20例;A组患者采用乳腺托架固定,B组患者采用乳腺托架联合U膜固定,C组患者采用真空垫联合翼型板固定。通过锥形束CT(CBCT)对3组患者的平移误差及加上旋转角度后导致的平移误差进行测量,并对测量结果进行统计学分析。结果平移误差:A组患者在X(左右)、Y(头脚)、Z(腹背)方向分别为(0.30±0.18)cm、(0.24±0.13)cm、(0.31±0.28)cm;B组患者在X、Y、Z方向的摆位误差分别为(0.17±0.10)cm、(0.23±0.24)cm、(0.23±0.19)cm;C组患者在X、Y、Z方向的摆位误差分别为(0.16±0.10)cm、(0.26±0.21)cm、(0.31±0.18)cm。加上旋转角度后的平移误差分别为:A组X、Y、Z方向分别为(0.29±0.23)cm、(0.27±0.18)cm、(0.33±0.26)cm,旋转误差分别为0.90°±1.10°、0.88°±0.98°、1.07°±1.19°;B组X、Y、Z方向分别为(0.17±0.09)cm、(0.21±0.15)cm、(0.25±0.20)cm,旋转误差分别为0.54°±0.55°、0.54°±0.36°、0.40°±0.28°;C组X、Y、Z方向分别为(0.18±0.14)cm、(0.34±0.22)cm、(0.24±0.14)cm,旋转误差分别为0.65°±0.42°、1.01°±0.55°、1.02°±0.61°。结果可见单纯的线性摆位误差,X方向上,B、C两组小于A组,P分别为0.010、0.007,差异有显著统计学意义(P≤0.01),其他方向与其他组别间的差异无统计学意义;加上旋转角度后导致的线性摆位误差,在X方向上,B组小于A组,P分别为0.044;在Y方向上,B组小于C组,P为0.038,差异有统计学意义(P<0.05);其他方向与其他组别间的差异无统计学意义。旋转角度中,B组在Z轴方向上小于A、C组,P为0.020、P<0.05,差异有统计学意义;B组在Y轴方向上小于C组,P为0.003,差异有显著统计学意义�
Objective To compare 3 different fixation methods of breast bracket,breast bracket combined U membrane and vacuum pad combined airfoil plate position fixation on setup errors in intensity-modulated radiotherapy(IMRT)for breast cancer,and explore suitable individualized fixation methods.Methods From June 2019 to May 2020,60 female breast cancer patients performed radiotherapy were enrolled,which aged 32-65 years old with median age of 45 years old.All of the patients were randomly divided into group A(n=20,fixed with breast bracket),B(n=20,fixed with breast bracket combined U membrane),and group C(n=20,fixed with vacuum pad combined airfoil plate).The cone beam CT(CBCT)was used to measure translation error and rotation angle caused translation error,and the results were statistically analyzed.Results The setup errors of group A were(0.30±0.18)cm,(0.24±0.13)cm and(0.31±0.28)cm at X(left-right),Y(superior-inferior)and Z(anterior-posterior),respectively;the setup errors of group B at X,Y and Z were(0.17±0.10)cm,(0.23±0.24)cm and(0.23±0.19)cm,respectively;the setup errors of group C at X,Y and Z were(0.16±0.10)cm,(0.26±0.21)cm and(0.31±0.18)cm,respectively.The translation errors caused by rotation angle of group A were(0.29±0.23)cm,(0.27±0.18)cm,(0.33±0.26)cm,and rotation errors were 0.90°±1.10°,0.88°±0.98°,1.07°±1.19°at X,Y,and Z,respectively.The translation errors caused by rotation angle of group B were(0.17±0.09)cm,(0.21±0.15)cm,(0.25±0.20)cm,and rotation errors were 0.54°±0.55°,0.54°±0.36°,0.40°±0.28°at X,Y,and Z,respectively.The translation errors caused by rotation angle of group C were(0.18±0.14)cm,(0.34±0.22)cm,(0.24±0.14)cm,and rotation errors were 0.65°±0.42°,1.01°±0.55°,1.02°±0.61°at X,Y,and Z,respectively.The linear setup error of group B and C was smaller than that of group A in X,and P value were 0.010,0.007,respectively,and the difference was statistically significant(P<0.01),the comparisons in other directions and other groups were not statistically signifi
作者
商在春
储开岳
葛彬彬
李明
朱琪伟
SHANG Zai-chun;CHU Kai-yue;GE Bin-bin;LI Ming;ZHU Qi-wei(Department of Radiation Oncology,Nantong Tumor Hospital,Nantong 226361,Jiangsu,China)
出处
《生物医学工程与临床》
CAS
2021年第4期415-420,共6页
Biomedical Engineering and Clinical Medicine
基金
南通市市级科技计划项目(MSZ20208)。
关键词
乳腺癌
放射治疗
固定装置
摆位误差
乳腺托架
U膜
真空垫
翼型板
breast cancer
radiotherapy
fixture
setup error
breast bracket
U membrane
vacuum pad
airfoil plate
