摘要
目的探究快速序贯器官功能评分(qSOFA)联合乳酸清除率(LCR)对感染性休克患者疾病严重程度及预后评估的价值。方法选择2017年1月~2020年1月接受治疗的60例感染性休克患者为研究组,另选取同期接受治疗的50例感染性疾病患者为对照组,对比两组患者入院第1天、第3天和第5天的qSOFA评分以及LCR。根据研究组患者预后情况将其分为死亡组(21例)和存活组(39例),对比两组患者入院后的qSOFA以及LCR,计算qSOFA、LCR与感染性休克患者血清降钙素原(PCT)相关性,绘制qSOFA和LCR对感染性休克预后评估ROC曲线,计算预测价值。结果研究组患者第3天及第5天的qSOFA评分均高于对照组,LCR均低于对照组(P<0.05);死亡组患者的qSOFA评分均高于存活组,LCR均低于存活组(P<0.05);相关性分析qSOFA与PCT呈正相关(r=0.8610,P<0.05),与LCR呈负相关(r=-0.9450,P<0.05);qSOFA、LCR与PCT的ROC曲线AUC分别为0.9590、0.8359、0.8125(P<0.05)。结论qSOFA评分联合LCR对感染性休克疾病严重程度具有较好的评估价值,还可以用于评估患者预后,以改善感染性休克患者生活质量。
Objective To explore the value of quick Sequential Organ Failure Assessment(qSOFA)combined with Clearance of lactic acid(LCR)in evaluating the severity and prognosis of patients with septic shock.Methods From January 2017 to January 2020,60 patients with septic shock who were treated in our hospital were the study group,and 50 patients with infectious diseases who were treated in our hospital during the same period were selected as the control group.The two groups were compared on the first day of admission.The qSOFA score and LCR on the 3rd and 5th days were divided into the death group(21 cases)and the survival group(39 cases)according to the prognosis of the patients in the study group.The qSOFA and LCR of the two groups of patients after admission were compared to calculate qSOFA and LCR correlation with serum procalcitonin(PCT)in patients with septic shock,draw the ROC curve of qSOFA and LCR to evaluate the prognosis of septic shock,and calculate the predictive value.Results The qSOFA scores of patients in the study group were both on the 3rd and 5th days higher than the control group,the LCR was lower than the control group(P<0.05);The qSOFA scores of the death group were higher than the survival group,and the LCR was lower than the survival group(P<0.05);Correlation analysis qSOFA was positively correlated with PCT(r=0.8610,P<0.05),and negatively correlated with LCR(r=-0.9450,P<0.05);The ROC curve AUC of qSOFA,LCR and PCT were 0.9590,0.8359,0.8125(P<0.05).Conclusion qSOFA score combined with LCR has a good evaluation value for the severity of septic shock disease,and can also be used to evaluate the prognosis of patients.It is recommended to promote clinical application to improve the quality of life of patients with septic shock.
作者
庾胜
YU Sheng(The second People’s Hospital of Changshu,Changshu 215500,China)
出处
《中国处方药》
2021年第8期183-186,共4页
Journal of China Prescription Drug
