摘要
目的:探讨老年慢性萎缩性胃炎中医证候与胃黏膜病理特征的相关性。方法:抽取2018年1月至2020年1月于鹤壁市中医院经内镜确诊为慢性萎缩性胃炎的378例患者为研究对象,为患者实施病理检查明确其胃黏膜病理特征,所有患者均接受中医辩证分型判定,观察分析中医症候分布规律,分析患者中医症候分布与胃黏膜病理特征的关系。结果:378例老年慢性萎缩性胃炎患者经胃黏膜病理检查结果显示,肠上皮化生程度:轻度156例,中度112例,重度110例;异型增生:轻度67例,中度164例,重度147例;患者经中医证型评估检出占比居前5位的分别为肝郁气滞证、脾胃湿热证、脾胃虚弱证、肝胃郁热证、胃阴不足证;胃阴不足和胃络淤阻证患者的肠上皮化生程度以轻度为主,胃络淤阻证患者的肠上皮化生程度以中度为主,胃阴不足证则以重度肠上皮化生常见,差异有统计学意义(P<0.05);不同中医证型的老年慢性萎缩性胃炎患者的轻度异型增生程度比较,差异未见统计学意义(P>0.05);脾胃虚弱证患者的中度异型增生占比最高,胃阴不足证患者的重度异型增生占比最高,差异有统计学意义(P<0.05)。结论:老年慢性萎缩性胃炎患者中医证候与胃黏膜病理特征之间有一定相关性。
Objective To investigate the correlation between traditional Chinese medicine(TCM)syndromes and pathological characteristics of gastric mucosa in elderly patients with chronic atrophic gastritis.Methods A totyal of 378 patients with chronic atrophic gastritis diagnosed by endoscopy in Hebi Hospital of Traditional Chinese Medicine from January 2018 to January 2020 were prospectively selected as the research subjects.Pathological examination was carried out to clarify the pathological characteristics of gastric mucosa,all the patients accepted TCM dialectical classification,the regularity of distribution of TCM syndromes was observed and analyzed,the relationship between distribution of TCM syndromes and pathological characteristics of gastric mucosa of patients was analyzed.Results In 378 cases of elderly patients with chronic atrophic gastritis,after the gastric mucosa pathological examination,the results showed that the degree of intestinal metaplasia:156 cases were mild,112 cases were moderate and 110 cases were severe;dysplasia:67 cases were mild,164 cases were moderate and 147 cases were severe;according to TCM syndrome type evaluation in patients,the proportion of top five were liver depression qi stagnation syndrome,spleen-stomach damp-heat syndrome,spleen-stomach weakness syndrome,liver-stomach heat-stagnation syndrome and stomach yin deficiency syndrome;the degree of intestinal metaplasia was mainly mild in patients with deficiency of stomach yin and stagnation of stomach collaterals,the degree of intestinal metaplasia in patients with stomach collateral stasis syndrome was mainly moderate,the difference was statistically significant(P<0.05);compared mild dysplasia in elderly patients with chronic atrophic gastritis of different TCM syndromes,the difference was not significant(P>0.05);moderate dysplasia accounted for the highest proportion in patients with spleen and stomach deficiency syndrome,the proportion of severe dysplasia in patients with stomach yin deficiency syndrome was the highest,the differen
作者
宋俊建
程玉舟
李学琴
Song Junjian;Cheng Yuzhou;Li Xueqin(Department of Geriatrics,Hebi Hospital of Traditional Chinese Medicine,Hebi 458030,China)
出处
《中国实用医刊》
2021年第12期46-48,共3页
Chinese Journal of Practical Medicine
关键词
胃炎
中医证候
胃黏膜
Gastritis
Traditional Chinese medicine syndromes
Gastric mucosa
