摘要
自2005年以来,不对称均相金催化反应研究取得了显著的进展,并在有机合成中得到了广泛应用.近年来,官能团化的联芳基单齿膦配体在金催化反应中显露头角,为不对称金催化反应提供了新的发展思路.本文综合评述了这一领域的研究进展,着重介绍了近年来利用这类配体实现的金催化不对称反应及反应过程中配体与底物间相互作用.
Homogeneous asymmetric gold catalysis had experienced remarkable development since 2005 andbeen applied extensively in organic synthesis.In the past several years,the development of chiral functiona-lized biaryl-2-ylphosphine ligands opens new approaches to achieving asymmetric gold catalysis.This reviewsummarizes several advances in this area and highlights the enabling interactions such as H-bonding,acid-base interaction,coulombic attraction,andπ-πstacking between ligand functional groups and substratesin asymmetric induction.
作者
赵可
洪志
张立明
ZHAO Ke;HONG Zhi;ZHANG Liming(Department of Chemistry and Biochemistry,University of California,Santa Barbara,CA 93106,USA;School of Pharmaceutical and Materials Engineering,Taizhou University,Taizhou 318000,China)
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
2021年第8期2324-2331,共8页
Chemical Journal of Chinese Universities
关键词
均相金催化
联芳基单齿膦配体
不对称反应
Homogeneous gold catalysis
Biaryl-2-ylphosphine ligand
Asymmetric reaction
