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电刺激在脑卒中后运动功能障碍治疗中的研究进展 被引量:9

Research Progress of Electric Stimulation in Treatment of Post-stroke Motor Dysfunction
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摘要 运动功能障碍是脑卒中发病后的主要并发症之一,表现为肢体麻木无力,甚至瘫痪或痉挛。运动功能障碍严重影响脑卒中患者的生活质量和社会参与度,因此针对运动功能的康复治疗对改善脑卒中患者预后尤为重要。电刺激作为一种新型的神经调控和外周传导技术,已逐渐应用于脑卒中患者的康复治疗中。不同方式的电刺激对皮质兴奋性的效果不同,其中脑深部电刺激、神经肌肉电刺激、经颅直流电刺激、经皮神经电刺激的作用最强,且具有选择性好、创口小、安全、直接等特点,具有促进脑卒中后运动功能恢复的巨大潜力。未来通过规范化的多中心试验,进一步完善电刺激具体实施标准和参数,将更好地满足运动功能障碍等临床康复治疗的需求。 Motor dysfunction is a major post-stroke complication,which is characterized by numbness and weakness of limbs,even paralysis or spasm.Motor dysfunction seriously affects the quality of life and social participation of the stroke patients,so the rehabilitation of motor function is particularly important to improve the prognosis.Electrical stimulation,as a new type of nerve regulation and peripheral conduction technology,has been gradually applied in the rehabilitation treatment of stroke.Different forms of electrical stimulation have different effects on cortical excitability.Among which deep brain electrical stimulation,neuromuscular electrical stimulation,transcranial direct current stimulation and transcutaneous electrical nerve stimulation are the most prominent electrical stimulation,with advantages such as good selectivity,small wounds,good safety and direct effect,showing great potential to promote motor function recovery after stroke.In the future,standardized multi-center trials will further improve the specific implementation standards and parameters of electrical stimulation,which will better meet the needs of the clinical rehabilitation treatment.
作者 李子洁 刘婷婷 吴铮 郑文荣 王宇峰 祝自新 田欣 郑瑞芳 邢建国 孙芳玲 王文 LI Zijie;LIU Tingting;WU Zheng;ZHENG Wenrong;WANG Yufeng;ZHU Zixin;TIAN Xin;ZHENG Ruifang;XING Jianguo;SUN Fangling;WANG Wen(Experimental Animal Center,Xuanwu Hospital of Capital Medical University,Beijing 100053,China;Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education,Zunyi Medical University,Zunyi 563006,China;Beijing Municipal Geriatrics Medical Research Center,Beijing 100053,China;Institute of Materia Medica of Xinjiang Uygur Autonomous Region,Urumqi 830011,China)
出处 《医学综述》 CAS 2021年第14期2796-2801,共6页 Medical Recapitulate
基金 国家自然科学基金(81503049)。
关键词 脑卒中 运动功能障碍 脑深部电刺激 神经肌肉电刺激 经颅直流电刺激 经皮神经电刺激 Stroke Motor dysfunction Deep brain stimulation Neuromuscular electrical stimulation Transcranial direct current stimulation Transcutaneous electrical nerve stimulation
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