摘要
目的:观察自拟方汤剂对胃癌术后化疗患者营养状态和免疫功能的影响。方法:选取80例胃癌术后化疗患者进行研究,按随机数字表法分为对照组、观察组,两组各40例。对照组采用肠内营养剂治疗,观察组采用肠内营养剂和自拟方汤剂治疗。结果:观察组骨髓抑制分级程度优于对照组(P<0.05)。治疗前两组患者血清总蛋白、白蛋白和前白蛋白差异不显著(P>0.05),治疗后两组患者血清总蛋白、白蛋白和前白蛋白均下降,观察组血清总蛋白、白蛋白和前白蛋白下降程度均低于对照组(P<0.05)。治疗前两组患者CD3+、CD4+、CD8+、CD4+/CD8+水平差异不显著(P>0.05),治疗后两组患者CD3+、CD4+、CD4+/CD8+水平均提高,CD8+水平下降;观察组CD3+、CD4+、CD4+/CD8+水平高于对照组,观察组CD8+水平低于对照组(P<0.05)。治疗前两组患者纳呆、便溏、腹胀、自汗、乏力和总分差异不显著(P>0.05),治疗后两组患者纳呆、便溏、腹胀、自汗、乏力和总分均下降;观察组纳呆、便溏、腹胀、自汗、乏力和总分均低于对照组(P<0.05)。结论:自拟方汤剂明显改善胃癌术后化疗患者营养状态,提高免疫功能。
Objective: To observe the effect of Self-made Decoction on the nutritional status and immune function for patients undergoing chemotherapy after gastric cancer surgery. Methods: 80 cases of gastric cancer patients undergoing chemotherapy after surgery were selected for the study. According to the random number table method, they were divided into a controlled group and an observation group, with 40 cases in each group. The controlled group was treated with enteral nutrition, and the observation group was treated with enteral nutrition and Self-made Decoction. Results: The grade of bone marrow suppression in the observation group was better than that in the controlled group(P<0.05). Before treatment, there was no significant difference in serum total protein, albumin and prealbumin between the two groups of patients(P>0.05). After treatment, the serum total protein, albumin and prealbumin of the two groups decreased. The observation group’s serum total protein and albumin, the decline of prealbumin and prealbumin were lower than those of the controlled group(P<0.05). Before treatment, there was no significant difference in the levels of CD3+,CD4+,CD8+,CD4+/CD8+ between the two groups of patients(P>0.05). After treatment, the levels of CD3+,CD4+,CD4+/CD8+ in the two groups increased, and the levels of CD8+ decreased;CD3+,CD4+,CD4+/CD8+ level the observation group was higher than that of the controlled group, and the CD8+ level of the observation group was lower than that of the controlled group(P<0.05). Before treatment, there was no significant difference in appetite, loose stools, abdominal distension, spontaneous sweating, fatigue, and total scores between the two groups of patients(P>0.05). After treatment, the two groups of patients had anorexia, loose stools, abdominal distension, spontaneous sweating, fatigue and total scores decreased. The observation group’s appetite, loose stools, abdominal distension, spontaneous sweating, fatigue and total score were lower than those of the controlled group(P<0.05).
作者
李梅
郝淑苹
李静
孙立明
LI Mei;HAO Shuping;LI Jing(Beijing Pinggu District Hospital,Pinggu Beijing 101200,China)
出处
《四川中医》
2021年第6期82-85,共4页
Journal of Sichuan of Traditional Chinese Medicine
关键词
胃癌
化疗
自拟方
营养状态
免疫功能
Gastric cancer
Chemotherapy
Self-made Decoction
Nutritional status
Immune function
