摘要
目的:探讨慢性阻塞性肺疾病急性加重(AECOPD)并发肺动脉高压(PH)的相关因素。方法:以2017年1月-2020年7月笔者所在医院152例AECOPD患者为研究对象,依据肺动脉压测量结果分为A组(肺动脉压正常的单纯AECOPD患者,83例)和B组(AECOPD合并PH患者,69例)。回顾性分析两组临床资料,观察指标差异,Logistic回归分析AECOPD并发PH危险因素。结果:B组SI、AST、PCT、NLR、RDW、NT-proBNP、PCO2、RIMP均高于A组,Pearson相关分析示与PH呈正相关性,FEV1%pred、FVC%pred均低于A组,Pearson相关分析示与PH呈负相关,差异有统计学意义(P<0.05)。Logistic回归分析显示,NLR、NT-proBNP、RIMP是AECOPD患者并发PH的独立危险因素。结论:NLR、NT-proBNP、RIMP对AECOPD并发PH具有较高预测价值,联合检测可以为AECOPD并发PH的临床诊断提供依据和参考。
Objective:To explore the related factors of pulmonary hypertension (PH) in acute exacerbation of chronic obstructive pulmonary disease (AECOPD).Method:Taking 152 AECOPD patients in our hospital from January 2017 to July 2020 as the research object,they were divided into group A (simple AECOPD patients with normal pulmonary artery pressure,83 cases) and group B (AECOPD patients with PH,based on the measurement results of pulmonary artery pressure,69 cases).The clinical data of the two groups were retrospectively analyzed,the differences in indicators were observed,and the risk factors of PH related to AECOPD were analyzed by Logistic regression.Result:The SI,AST,PCT,NLR,RDW,NT-proBNP,PCO2 and RIMP of group B were all higher than those of group A.Pearson correlation analysis showed positive correlation with PH.FEV1%pred and FVC%pred were lower than group A.Pearson correlation analysis showed negative correlation with PH Correlation,the difference was statistically significant (P<0.05).Logistic regression analysis showed that NLR,NT-proBNP and RIMP were independent risk factors for PH in patients with AECOPD.Conclusion:NLR,NT-proBNP and RIMP have high predictive value for AECOPD complicated with PH,and combined detection can provide basis and reference for the clinical diagnosis of AECOPD complicated with PH.
作者
冼美兰
黄奕荣
邱潮锋
郭楚杰
XIAN Meilan;HUANG Yirong;QIU Chaofeng;GUO Chujie(Dafeng Hospital of Chaoyang District in Shantou,Shantou 515154,China;不详)
出处
《中外医学研究》
2021年第18期153-155,共3页
CHINESE AND FOREIGN MEDICAL RESEARCH
关键词
慢性阻塞性肺疾病
急性加重
肺动脉高压
因素
Chronic obstructive pulmonary disease
Acute exacerbation
Pulmonary hypertension
Factors
