摘要
目的:探究感恩-拓展理论行为对乳腺癌化疗患者复发恐惧的影响。方法:选取2018年1月至2019年12月在扬州大学附属医院接受治疗的154位乳腺癌患者作为研究对象,依据患者疾病分期将其分为A_(1)组、A_(2)组、B_(1)组和B_(2)组,A_(1)组为进行常规行为指导干预的Ⅰ期、Ⅱ期患者;A_(2)组为进行感恩-拓展理论行为指导干预的Ⅰ期、Ⅱ期患者;B_(1)组为进行常规行为指导干预的Ⅲ期,Ⅳ期患者;B_(2)组为进行感恩-拓展理论行为指导干预的Ⅲ期、Ⅳ期患者。对比A_(1)、A_(2)两组患者手术后6个月后无病生存率、总生存率、局部复发率及远处转移率,并采用癌症患者恐惧疾病进展简化量表(fear of progression questionnaire-short form,FoP-Q-SF)对癌症复发的恐惧进行评价;对比B_(1)、B_(2)两组患者化疗后癌症病灶进展情况并采用FoP-Q-SF评价其对癌症复发的恐惧。结果:术后6个月对A_(1)、A_(2)两组进行随访,A_(1)组患者无病生存率、总生存率与A_(2)组无统计学意义(P>0.05)。对B_(1)、B_(2)两组患者治疗后疾病进展作统计,B_(2)组患者化疗后疾病缓解率为75.00%,疾病控制率为93.18%,显著高于对照组患者,差异具有统计学意义(P<0.05)。A_(1)组术后FoP-Q-SF评分为30.63±4.01,A_(2)组术后FoP-Q-SF评分为27.37±4.32;B_(1)组术后FoP-Q-SF评分为32.33±5.34,B_(2)组术后FoP-Q-SF评分为29.45±4.27。各组间差异具有统计学意义(PA<0.05,PB<0.05)。结论:感恩-拓展理论行为可降低乳腺癌化疗患者对疾病复发的恐惧感,提高治疗对患者疾病的控制率,帮助患者调整心态,以积极乐观的心态对抗病魔。
Objective:To explore the effect of gratitude-expansion theory behavior on the fear of recurrence of breast cancer chemotherapy patients.Methods:A total of 154 breast cancer patients who were treated in Affiliated Hospital of Yangzhou University from January 2018 to December 2019 were selected as the research objects,and they were divided into groups A_(1),A_(2),B_(1),and B_(2) according to their disease stages.Group A_(1) was stage Ⅰ and stage Ⅱ patients undergoing routine behavioral guidance intervention;group A_(2) was stage Ⅰ and stage Ⅱ patients undergoing gratitude-expension theoretical behavioral guidance intervention;group B_(1) was stage Ⅲ and stage Ⅳ patients undergoing conventional behavioral guidance intervention;group B_(2) was stage Ⅲ and Ⅳ patients undergoing gratitude-expansion theoretical behavior guidance intervention.The disease-free survival rate,overall survival rate,local recurrence rate and distant metastasis rate of patients in group A_(1) and group A_(2) after surgery were compared,and patients’cancer recurrence fear was evaluated by using the fear of progression questionnaire-short form(FoP-Q-SF);the progress of cancer lesions after chemotherapy was compared between patients in groups B_(1) and B_(2),and the FoP-Q-SF was used to evaluate their fear of cancer recurrence.Results:The A_(1) and A_(2) groups were followed up for 6 months after the operation.The disease-free survival rate and overall survival rate of the A_(1) and A_(2) group was not statistically significant(P>0.05).The disease progression of patients in groups B_(1) and B_(2) after treatment was analyzed.In group B_(2),the disease remission rate after chemotherapy was 75.00%,and the disease control rate was 93.18%,which was significantly higher than that of the control group.The difference was statistically significant(P<0.05).The postoperative FoP-Q-SF score in group A_(1) was(30.63±4.01),and the postoperative FoP-Q-SF score in group A_(2) was(27.37±4.32);the postoperative FoP-Q-SF score in group B_(1) wa
作者
陆美玲
陈英梅
郭霖
王兆锦
LU Meiling;CHEN Yingmei;GUO Lin;WANG Zhaojin(Department of Oncology,Affiliated Hospital of Yangzhou University,Yangzhou Jiangsu 225009;Department of Breast Surgery,Affiliated Hospital of Yangzhou University,Yangzhou Jiangsu 225009,China)
出处
《临床与病理杂志》
CAS
2021年第7期1579-1585,共7页
Journal of Clinical and Pathological Research
关键词
感恩-拓展理论
乳腺癌
化疗
复发恐惧
gratitude-expansion theory
breast cancer
chemotherapy
fear of relapse
