摘要
目的比较地屈孕酮与左炔诺孕酮宫内节育系统辅助宫腔下镜子宫内膜息肉切除术(TCRP)治疗子宫内膜息肉的临床效果。方法138例子宫内膜息肉患者,随机分为观察组与参照组,各69例。两组均进行TCRP治疗,参照组实行地屈孕酮辅助治疗,观察组实行左炔诺孕酮宫内节育系统辅助治疗。对比两组治疗前后的子宫内膜厚度、月经量评分、临床复发率、疗效。结果治疗后,观察组的子宫内膜厚度(1.94±0.78)mm、月经量评分(31.36±1.17)分,均低于参照组的(4.57±1.06)mm、(45.61±2.35)分,差异有统计学意义(P<0.05)。观察组复发率2.90%低于参照组的17.39%,差异有统计学意义(P<0.05)。观察组的治疗总有效率95.65%高于参照组的84.06%,差异有统计学意义(P<0.05)。结论通过对子宫内膜息肉患者实行左炔诺孕酮宫内节育器系统辅助TCRP治疗,其可以有效降低子宫内膜厚度,改善月经,对于降低子宫内膜息肉复发率以及提高临床治疗有效率都是极为有利的。
Objective To compare the clinical effects of hysteroscopic transcervical resection of polyp(TCRP)aided with dydrogesterone and levonorgestrel intrauterine system on the treatment of endometrial polyps.Methods 138 patients with endometrial polyps were randomly divided into an observation group and a control group,with 69 patients in each group.The two groups were treated with TCRP.The control group was treated with aid of dydrogesterone,and the observation group was treated with aid of levonorgestrel intrauterine system.The endometrial thickness,menstrual volume score,clinical recurrence rate and therapeutic efficacy prior and after treatment were compared between these two groups.Results After treatment,the observation group had an endometrial thickness of(1.94±0.78)mm,menstrual volume score of(31.36±1.17)points,which were lower than(4.57±1.06)mm,(45.61±2.35)points of the control group,the difference was statistically significant(P<0.05).The clinical recurrence rate of the observation group was 2.90%,which was lower than 17.39%of the control group,and the difference was statistically significant(P<0.05).The overall therapeutic efficacy of the observation group was 95.65%,which was higher than 84.06%of the control group,the difference was statistically significant(P<0.05).Conclusion TCRP aided with levonorgestrel intrauterine system can effectively reduce the endometrial thickness and improve menstruation.Thus,it is advantageous to reduce the recurrence rate of endometrial polyps and improve the therapeutic efficacy of clinical treatment.
作者
石雪金
彭祥菊
张璐
SHI Xue-jin;PENG Xiang-ju;ZHANG Lu(Zengcheng Maternal and Child Health Hospital,Guangzhou 511300,China)
出处
《中国现代药物应用》
2021年第14期145-147,共3页
Chinese Journal of Modern Drug Application
