摘要
目的探讨中性粒细胞相关参数在下肢深静脉血栓形成(lower extremity deep venous thrombosis,LEDVT)的临床应用价值。方法选取2017年6月到2020年6月177例在广西医科大学附属第四医院首诊为LEDVT形成的患者为观察组,记录其入院第1天和接受治疗2周后的中性粒细胞百分数(N%)、中性粒细胞绝对值(N)、中性粒细胞绝对值/淋巴细胞绝对值(NLR),并将患者按发病时间分为急性组和慢性组;177例同期健康体检者为对照组。比较分析各组各个指标的价值。结果观察组的N%、N、NLR均明显高于对照组,差异有统计学意义(P<0.01)。N和NLR联合诊断LEDVT的灵敏度是85.9、特异度是65.4,ROC是0.858。治疗后各指标均有明显下降。结论 N联合NLR在LEDVT的诊断中有一定意义,动态观察中性粒细胞N%、N、NLR参数可以预测疗效。
Objective To explore the value of neutrophil-related parameters in the diagnosis of lower extremity deep venous thrombosis(LEDVT).Methods 177 patients of LEDVT whose percentage of neutrophils(N%),absolute neutrophils(N),absolute neutrophils/absolute lymphocytes(NLR)were record at the first day of admission and two weeks after receiving treatment were initially diagnosed from June 2017 to June 2020 as the observation group,and divided into acute group and chronic group according to the onset time.177 healthy people in the same period were chosen as the control group.The values of neutrophil-related parameters in each group were compared and analyzed.Results The N%,N,and NLR in the LEDVT group were significantly higher than those in the control group(P<0.01).The sensitivity,specificity and ROC of the combined N and NLR were 85.9%,65.4%,0.858.All indicators decreased significantly after treatment.Conclusion N combined with NLR is a simple and convenient screening method with certain clinical value in the diagnosis of LEDVT,and dynamic observation of neutrophil parameters can predict the therapeutic effect.
作者
张巧云
李音音
蒙杰
邓开凤
ZHANG Qiaoyun;LI Yin-yin;MENG Jie(Medical Science Laboratory,the Fourth Affiliated Hospital of Guangxi Medical University,Liuzhou 545005,China)
出处
《中国实验诊断学》
2021年第6期833-836,共4页
Chinese Journal of Laboratory Diagnosis
关键词
中性粒细胞参数
下肢深静脉血栓形成
临床意义
neutrophil-related parameters
lower extremity deep venous thrombosis
clinical significance
