摘要
One of the key challenges in neuroscience is that the central nervous system(CNS;the brain and spinal cord), is largely unable to regene rate after injury. One factor contributing to this lack of repair is the accumulation of cellular and myelin debris at the site of injury. The debris is not efficiently phagocytosed and can persist for years after the initial injury, resulting in an inflammatory environment which inhibits axonal regrowth(Lutz and Barres, 2014).
基金
supported by a Garnett-Passe and Rodney Williams Memorial Foundation Grant to JE
a National Health and Medical Research Council Grant to JS and JE(grant No.APP1183799)
a Motor Accident Insurance Commission Queensland Grant to JS and JE
a Perry Cross Foundation Grant to JE and JS
a Clem Jones Foundation grant to JS and JE。
