摘要
肝细胞癌是肝脏最常见的恶性肿瘤,当肝细胞癌出现微血管侵犯,提示患者预后不佳,是肿瘤复发和肿瘤进展的独立危险因素之一。目前微血管侵犯仅仅依靠术后病理组织学活检明确,如果能够在术前预测微血管侵犯的发生,对调整手术模式,优化诊疗计划,制定个体化的治疗方案有巨大的帮助。影像学检查在肿瘤整体观上有独特的优势,能够弥补穿刺活检中不能体现出肿瘤不同部分细胞的空间异质性及随诊复查过程中肿瘤变化的时间异质性。随着影像学检查的发展,尤其是影像组学的发展,影像能够大量的提取人类肉眼不能区分的信息,大量的特征信息使影像学预测模型有着很大的应用前景,本文对影像学检查术前预测肝细胞肝癌微血管侵犯的研究进展进行文献的回顾和综述。
Hepatocellular carcinoma is the most common malignant tumor of the liver.When hepatocellular carcinoma has microvascular invasion,it indicates poor prognosis of patients and it is one of the independent risk factors for tumor recurrence and progression.At present,microvascular invasion is only detected by postoperative histopathological biopsy.If the occurrence of microvascular invasion can be predicted preoperatively,it will be of great help to adjust the surgical way,optimize the diagnosis and treatment plan,and formulate the individualized treatment plan.Imaging examination has a unique advantage in the overall view of tumor,which can make up for the failure of puncture biopsy to reflect the spatial heterogeneity of different parts of tumor cells and the temporal heterogeneity of tumor changes during follow-up review.With the development of imaging examination,especially the development of radiomics,a large amount of information of human eye cannot distinguish can be extracted,and a lot of characteristic information make imaging prediction model has a great application prospect.This paper reviews and summarizes the research progress in the imaging examination preoperative forecast HCC microvascular invasion.
作者
杨凡(综述)
陈晓东
罗树存
罗泽斌(审校)
YANG Fan;CHEN Xiao-dong;LUO Shu-cun;LUO Ze-bin(Guangdong Medical University,Zhanjiang 524000,Guangdong,CHINA;Department of Radiology,the Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,Guangdong,CHINA)
出处
《海南医学》
CAS
2021年第14期1881-1885,共5页
Hainan Medical Journal
关键词
肝细胞癌
微血管侵犯
影像学检查
影像组学
纹理特征
临床应用
Hepatocellular carcinoma(HCC)
Microvascular invasion
Imaging examination
Radiomics
Textural features
Clinical application
