摘要
目的探讨老年冠心病(CHD)患者应用阿司匹林抗血小板治疗并发上消化道出血的独立危险因素。方法选取2016年1月—2020年10月在抚州市东乡区人民医院就诊的100例老年CHD患者,观察其阿司匹林治疗期间上消化道出血情况,统计患者一般资料,分析CHD患者并发上消化道出血的独立危险因素。结果 100例CHD患者阿司匹林治疗期间,并发上消化道出血率46.00%(46/100);经单因素与多因素分析,提示年龄≥65岁、消化道疾病史、吸烟史、饮酒史、服药时间>3个月、服药剂量300 mg/d、未使用胃黏膜保护剂均是导致CDH患者抗血小板治疗期间并发上消化出血的独立危险因素(P<0.05)。结论老年CHD患者应用阿司匹林抗血小板治疗并发上消化道出血的危险因素较多,临床需加强防治,以改善患者预后。
Objective To investigate the independent risk factors of the application of aspirin antiplatelet in the treatment of combined upper gastrointestinal bleeding in elderly patients with coronary heart disease(CHD).Methods 100 elderly patients with CHD treated in our hospital from January 2016 to October 2020 were selected,the upper gastrointestinal bleeding of patients was observed during aspirin treatment.The general data of patients were collected,the independent risk factors of combined upper gastrointestinal bleeding in patients with CHD were analyzed.Results Of 100 cases of patients with CHD during aspirin treatment,46.00%(46/100)were complicated with upper gastrointestinal bleeding,univariate and multivariate analysis showed that age≥65 years old,history of gastrointestinal diseases,smoking history,drinking history,medication time>3 months,dosage of 300mg/d,and no use of gastric mucosal protectants were the risk factors of combined upper digestive bleeding in patients with CDH during antiplatelet therapy(P<0.05).Conclusion There are many risk factors of combined upper gastrointestinal bleeding in elderly CHD patients with the application of aspirin antiplatelet therapy,it is necessary to strengthen the prevention and treatment work clinically in order to improve the prognosis of patients.
作者
饶锋刚
杨丽娟
梁云
Rao Fenggang;Yang Lijuan;Liang Yun(The Dongxiang District People’s Hospital of Fuzhou City,Fuzhou,Jiangxi 331800)
出处
《基层医学论坛》
2021年第20期2815-2817,共3页
The Medical Forum
基金
2020年度第一批市级指导性科技计划项目(抚科计字{2020}10号第110号)。
关键词
冠心病
老年患者
阿司匹林
上消化道出血
独立危险因素
Coronary heart disease
Gerontal patient
Aspirin
Upper gastrointestinal bleeding
Independent risk factor
