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光学表面监测系统引导实现左侧乳腺癌深吸气屏气治疗临床应用及评估 被引量:11

Application and evaluation of OSMS guided DIBH radiotherapy for left-sided breast cancer
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摘要 目的:通过分析摆位精度、摆位时间和心脏位置评估以光学表面监测系统(OSMS)引导实现左侧乳腺癌深吸气屏气(DIBH)治疗的临床价值。方法:30例左侧乳腺癌保乳术后患者,运用OSMS的“Move Couch”自动摆位功能,以OSMS引导摆位、DIBH和治疗监控,实现DIBH技术治疗。分析CBCT配准靶区六维绝对误差数据和心脏位置的误差数据,记录摆位时间。结果:绝对摆位误差在x、y、z平移方向和Rx、Ry、Rz旋转方向分别为(0.11±0.08)、(0.14±0.11)、(0.13±0.10)cm和(0.79±0.66)、(0.69±0.57)、(0.73±0.64)°。心脏位置在x、y、z方向平移误差分别为(0.01±0.30)、(0.05±0.34)、(0.01±0.09)cm。摆位时间为(4.1±1.2)min。结论:左侧乳腺癌DIBH放疗技术可将心脏向下、后方推移,远离放疗靶区,减少心脏受量。基于OSMS实施左侧乳腺癌DIBH治疗实现了较好的靶区和心脏位置准确性,OSMS的自动摆位功能可帮助提高摆位精度,减少摆位时间。 Objective To evaluate the clinical value of optical surface monitoring system(OSMS)guided deep inspiration breath hold(DIBH)radiotherapy for left-sided breast cancer by analyzing positioning accuracy,setup time and cardiac position.Methods Thirty patients with left-sided breast cancer after breast-conserving surgery were enrolled in the study.The Move Couch function of OSMS was used for automatic positioning,and DIBH radiotherapy was realized based on OSMS guided positioning,DIBH and treatment monitoring.After CBCT registration,the six-dimensional absolute errors of target areas and the errors of cardiac position were analyzed,and meanwhile the setup time which was defined as the time from the patient's contact with the couch to the time before CBCT scanning or before accelerator beam on(without CBCT scanning)was recorded.Results The absolute setup errors were(0.11±0.08),(0.14±0.11),(0.13±0.10)cm in x,y,z directions,respectively,and(0.79±0.66)°,(0.69±0.57)°,(0.73±0.64)°in Rx,Ry,Rz directions,respectively.The averages of cardiac position deviations were(0.01±0.30),(0.05±0.34),(0.01±0.09)cm in x,y,z directions.The recorded setup time was(4.1±1.2)min.Conclusion DIBH technique for left-sided breast cancer makes the heart distant from treatment target area by moving the heart to posterior and inferior directions,thereby lowering the radiation dose delivered to the heart.OSMS guided DIBH radiotherapy for left-sided breast cancer results in a good positioning accuracy of target areas and the heart.The automatic positioning function of OSMS contributes to improving positioning accuracy and reducing setup time.
作者 张光伟 钟鹤立 吴何苟 刘剑锋 张定 杨东 樊娟 李彬 徐广然 ZHANG Guangwei;ZHONG Heli;WU Hegou;LIU Jianfeng;ZHANG Ding;YANG Dong;FAN Juan;LI Bin;XU Guangran(Department of Radiation Oncology,Shenzhen People's Hospital(the Second Clinical Medical College of Ji'nan University,the First Affiliated Hospital of Southern University of Science and Technology),Shenzhen 518020,China)
出处 《中国医学物理学杂志》 CSCD 2021年第7期793-797,共5页 Chinese Journal of Medical Physics
基金 国家自然科学基金(61871374) 深圳市科技研发基金(JCYJ20170307145422811)。
关键词 光学表面监测系统 放射治疗 左侧乳腺癌 深吸气屏气 自动摆位 optical surface monitoring system radiotherapy left-sided breast cancer deep inspiration breath hold automatic positioning
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