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胰管外引流与早期肠内营养在胰十二指肠切除术中的应用疗效分析 被引量:3

Analysis of the Effect of External Pancreatic Duct Drainage and Early Enteral Nutrition in Pancreaticoduodenectomy
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摘要 目的分析胰管外引流与早期肠内营养在胰十二指肠切除术中的应用疗效。方法该次研究以该院2016年1月—2019年12月收治的30例十二指肠癌及壶腹部周围恶性肿瘤患者为研究对象,此次参与研究的患者均接受胰十二指肠切除术,并给予患者胰管外引流及早期肠内营养,观察并分析此次参与研究的患者经手术治疗后,相关并发症发生情况及术后各时间点白蛋白、总胆红素、血淀粉酶水平,分析胰管外引流及早期肠内营养改善胰十二指肠切除术患者术后各项并发症发生情况,及促进患者胃肠功能恢复的临床效果。结果此次参与研究的患者中,30例均完成手术并顺利出院,手术病死率为0.0%;其中2例患者出现A级胰瘘,发生率为6.67%,无术后出血患者,2例患者出现其他并发症,发生率为6.67%,此次参与研究的患者总并发症发生率为13.33%(4/30);此次参与研究的患者术后1 d的白蛋白水平低于术前,术后7 d的白蛋白水平高于术后1 d,各项数据差异有统计学意义(P<0.05)。术后7 d的白蛋白水平低于术前,差异无统计学意义(P>0.05);所有患者术后1 d总胆红素水平与术前相比差异无统计学意义(P>0.05),但术后7 d时总胆红素水平明显下降,数据差异有统计学意义(P<0.05);此次参与研究的患者术后1 d及术后7 d血淀粉酶水平数据差异无统计学意义(P>0.05)。结论胰管外引流及早期肠内营养能有效改善胰十二指肠切除术患者胰瘘、出血等各项术后并发症发生情况,促进机体胃肠功能恢复。 Objective To analyze the effect of external pancreatic duct drainage and early enteral nutrition in pancreaticoduodenectomy.Methods This study took 30 patients with duodenal cancer and malignant tumors around the ampulla who were admitted to the hospital from January 2016 to December 2019 as the research objects.The patients participating in the study all received the pancreaticoduodenum resection,and give patients extra-pancreatic duct drainage and early enteral nutrition.Observed and analyzed the occurrence of related complications and albumin,total bilirubin,blood at various time points after surgery in the patients participating in the study.The level of amylase was analyzed to analyze the clinical effects of external pancreatic duct drainage and early enteral nutrition to improve the occurrence of various complications after pancreaticoduodenectomy and to promote the recovery of gastrointestinal function in patients.Results Among the patients participating in the study,30 patients completed the operation and were discharged successfully.The operative mortality rate was 0.00%.Among them,2 patients developed grade A pancreatic fistula,and the incidence was 6.67%in patients without postoperative bleeding,and 2 patients had other complications,the incidence rate was 6.67%,the total complication rate of the patients participating in the study was 13.33%(4/30);the albumin level of the patients participating in the study was lower than 1 d after surgery than that before surgery,the albumin level of 7 d after operation was higher than that of 1 d after operation,and the difference in the data was statistically significant(P<0.05).The albumin level at 7 days after operation was lower than that before operation,and the difference was not statistically significant(P>0.05);the total bilirubin level of all patients at 1 d after operation was not significantly different from that before operation,and there was no statistically significant difference in data(P>0.05),but the total bilirubin level was significantly decreased
作者 王代韦 张继福 WANG Daiwei;ZHANG Jifu(Department of General Surgery,Wenshan Prefecture People's Hospital,Wenshan,Yunnan Province,663000 China)
出处 《世界复合医学》 2021年第5期1-3,11,共4页 World Journal of Complex Medicine
关键词 胰管外引流 早期肠内营养 胰十二指肠切除术 胰瘘 External pancreatic duct drainage Early enteral nutrition Pancreaticoduodenectomy Pancreatic fistula
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