摘要
目的分析孤独症筛查量表对婴幼儿筛查效果及影响因素.方法选取2020年10月~2021年3月我院孤独症婴幼儿210例作为孤独症组,并以1:1配比选取同期我院发育正常的婴幼儿210例作为健康对照组,均采用孤独症婴幼儿筛查量表修订版(M-CHAT)进行筛查,统计筛查效果,并收集两组儿童临床信息,分析婴幼儿发生孤独症的影响因素.结果210例孤独症婴幼儿,四周后电话回访结果判定阳性203例,阴性7例,灵敏度96.67%(203/210);210例发育正常婴幼儿中,四周后电话回访结果判定阳性3例,阴性207例,特异度98.57%(207/210).胎龄、出生体重、有无围生期窒息史、有无缺氧缺血性脑病史、有无染色体畸形等先天疾患、母亲有无不良孕产史、母亲有无妊娠期合并症、母亲有无代谢性疾病、父母文化程度、家庭人均月收入、主要抚养人、母亲喂养条件是婴幼儿发生孤独症的影响因素(P<0.05);logistic回归分析显示,胎龄<37周、出生体重<2500g、围生期窒息史、缺氧缺血性脑病史、合并染色体畸形等先天疾患、母亲有不良孕产史、母亲有妊娠期合并症、母亲有代谢性疾病、父母文化程度低、家庭人均月收入少、主要抚养人非父母、母亲喂养条件差为婴幼儿发生孤独症的危险因素(P<0.05).结论M-CHAT在筛查婴幼儿孤独症中应用效果显著,灵敏度和特异度较高,且婴幼儿发生孤独症的危险因素较多,临床应根据上述因素针对性实施干预措施,降低孤独症发生风险.
Objective To analyze the effect and influencing factors of autism screening scale on infant screening.Met hods 210 autistic infants and children in our hospital from October 2020 to March 2021 were selected as the autism group.210 infants with normal development in our hospital were selected as the control group with 1:1 ratio.All of them were screened with M-CHAT,and the results were statistically analyzed.The clinical information of the two groups of children was collected to analyze the effects of autism in infants and children The impact factor.Results 210 autistic infants were positive,203 were positive after four weeks,7 were negative,and the sensitivity was 96.67%(203/210);among 210 normal infants,3 were positive after four weeks,207 were negative,and the specificity was 98.57%(207/210).The factors influencing autism are gestational age,Birth weight,perinatal asphyxia,history of hypoxic-ischemic encephalopathy,chromosome abnormality,and other congenital diseases,whether the mother has a history of bad pregnancy and child birth,whether the mother has pregnancy complications,whether the mother has metabolic disease,parents'education level,monthly income per family,main support and feeding conditions of mother(P<0.05).Logistic regression analysis showed that the birth age was less than 37 weeks,birth weight was less than 2500g,perinatal asphyxia,hypoxic-ischemic encephalopathy,chromosome malformation,etc.,mother had a history of bad pregnancy and labor,mother had pregnancy complications,mother had metabolic diseases,low parents'education,low per capita income per capita,ncn parents of main support,poor feeding conditions of mother The risk factors of autism in infants(P<0.05).Concusion M-CHAT has a significant effect in screening autism in infants,with high sensitivity and specificity,and there are many risk factors for autism in infants.Therefore,intervention measures should he implemented according to the above factors in order to reduce the risk of autism.
作者
刘爱军
Liu Aijun(Child care depar tment,women and children health and family planning service center,Jizhou District,Tianjin 301900)
出处
《首都食品与医药》
2021年第13期23-25,共3页
Capital Food Medicine
