摘要
目的探讨单中心儿童肝移植手术方式、围术期管理对患者临床结局的影响。方法纳入青岛大学附属医院器官移植中心自2016年1月—2021年1月25例儿童肝移植患者临床资料,观察患者的一般结果、术后外科并发症以及预后。结果本组25例患儿中,3例患儿术后2个月内死亡,门静脉狭窄2例,肝功能延迟恢复1例,术后2个月生存率为86.4%,1年生存率为86.4%,随访至今,22例存活患儿的移植物均恢复良好,免疫抑制剂药物浓度维持在稳定区间。结论本中心儿童肝移植的手术成功率及术后生存率尚可,仍需加强围术期管理,以期获得更好的远期存活效果。
Objective To explore the influence of surgical methods and perioperative management on clinical outcomes of pediatric liver transplantation in a single center.Methods The clinical data of 25 pediatric liver transplantation patients from January 2016 to January 2021 in organ transplantation center of the Affiliated Hospital of Qingdao University were included to observe the general results,postoperative surgical complications and prognosis.Results Among the 25 cases,3 cases died within 2 months after operation,2 cases experienced portal vein stenosis and 1 case experience delayed recovery of liver function.The postoperative 2-month survival rate was 86.4%,and the 1-year survival rate was 86.4%.Up to now,the graft function of 22 patients recovered well,and the immunosuppressant concentration remained in a stable range.Conclusion The success rate and survival rate of pediatric liver transplantation in our center are acceptable,and it is still necessary to strengthen perioperative management in order to achieve better long-term survival results.
作者
李天翔
孙延东
李志强
刘单
滕大洪
吴斌
刘虹
李新强
蔡金贞
Li Tianxiang;Sun Yandong;Li Zhiqiang;Liu Dan;Teng Dahong;Wu Bin;Liu Hong;Li Xinqiang;Cai Jinzhen(Organ Transplantation Center,Affiliated Hospital of Qingdao university,Qingdao 266000,China)
出处
《实用器官移植电子杂志》
2021年第4期299-303,共5页
Practical Journal of Organ Transplantation(Electronic Version)
关键词
肝移植
儿童
劈离式肝移植
多米诺肝移植
预后
Liver transplantation
Children
Split liver transplantation
Domino liver transplantation
Prognosis
