摘要
目的:比较分析家族聚集性前庭性偏头痛(FCVM)与散发性前庭性偏头痛(SVM)患者的临床特征。方法:选取118例前庭性偏头痛患者,根据有无家族聚集性发病分为FCVM组(66例)和SVM组(52例),分析比较两组患者的发病年龄、症状形式、影响因素、听力学症状、发作后遗症及合并症。结果:FCVM组患者的头痛发病年龄较SVM组早[分别为(23.88±11.45)岁和(28.77±11.85)岁,χ^(2)=2.267,P=0.025],间隔时间较长[分别为(13.11±10.08)岁和(8.50±9.26)岁,χ^(2)=2.554,P=0.012]。FCVM组表现位置性眩晕患者较SVM多[分别为12例(18.2%)和0(0),χ^(2)=3.171,P=0.002]。相比于SVM患者,精神焦虑(P<0.001)、颈部僵直(P=0.028)及注意力难以集中(P=0.001)在FCVM患者发作后期更为多见。FCVM组合并原发性晕动病患者多于SVM组[分别为49例(74.2%)和25例(48.1%),χ^(2)=2.906,P=0.004]。结论:FCVM患者的发病年龄较早,多预后不良。原发性晕动病可作为FCVM早期诊断的参考指标。
Objective: To compare and analyze the clinical features of family clustered vestibular migraine(FCVM) and sporadic vestibular migraine(SVM). Methods: A total of 118 patients with vestibular migraine were selected and divided into FCVM group(66 cases) and SVM group(52 cases), and the clinical features such as age, the form of symptoms, provoking and relieving factors, audiological manifestations, sequelae and complications, were compared and analyzed. Results: The onset of headache in FCVM group was earlier than that in SVM group([23.88±11.45] years old and [28.77±11.85] years old, χ^(2)=2.267, P=0.025) with a longer interval between headache and vertigo attack([13.11±10.08] years old and [8.50±9.26] years old, χ^(2)=2.554, P=0.012).Patients with positional vertigo in the FCVM group were more than those in the SVM group(12[18.2%] and 0[0], χ^(2)=3.171, P=0.002). Mental anxiety(P<0.001), neck stiffness(P=0.028), and concentration difficulties(P=0.001) were more common in patients with FCVM at the end of the episode than in patients with SVM. Comorbid primary motion sickness combined was more common in FCVM group than in SVM group(49 cases[74.2%] and 25 cases[48.1%], χ^(2)=2.906, P=0.004). Conclusion: The onset of FCVM is earlier and the prognosis is often poor. Primary motion sickness can be used as a reference for the early diagnosis of FCVM.
作者
冯慧敏
金占国
刘红巾
徐先荣
翟丽红
王蒙
章梦蝶
FENG Huimin;JIN Zhanguo;LIU Hong jin;XU Xianrong;ZHAI Lihong;WANG Meng;ZHANG Mengdie(Aerospace Balance Medical Center,Chinese PLA Air Force Medical Center,Beijing,100142,China;Department of Medical Identification,Chinese PLA Air Force Medical Center)
出处
《临床耳鼻咽喉头颈外科杂志》
CSCD
北大核心
2021年第6期525-528,共4页
Journal of Clinical Otorhinolaryngology Head And Neck Surgery
基金
军队后勤和军内科研重点资助项目(No:KJ20191A050325,No:BKJ19J020)
空军军医大学科技攻关资助项目(No:2019ZTC02)。
关键词
前庭性偏头痛
家族聚集性
临床特征
晕动病
vestibular migraine
family clustered
clinical features
motion sickness
