摘要
[目的]发现高除草活性化合物。[方法]通过亚结构拼接,设计合成了一系列芳氧苯氧丙酸酰胺类化合物。[结果]生测数据显示,大多数化合物在15 g a.i./hm2剂量下对稗草的防效大于80%,其中化合物1a和1b防效大于95%。[结论]设计合成的化合物均具有较好的活性。构效关系显示,随着氮氧杂环上碳原子个数的增加,活性有降低的趋势。
[Aims] This study aims to discover new herbicidal compounds with high activity. [Methods] A series of aryloxyphenoxypropanamide compounds were designed and synthesized by substructural splicing. [Results] Preliminary bioassay indicated that most compounds exhibited more than 80% control against Echinochloa crus-galli at 15 g a.i./ha,and 1 a and 1 b exhibited more than 80% control against E. crus-galli. [Conclusions] The designed compounds all showed good herbicidal activity. The structure-activity relationship indicated that the activity tended to decrease with the increase of the number of carbon atoms in the nitrogen and oxygen heterocycle.
作者
梁爽
刘鹏飞
程学明
张孟迪
李斌
杨辉斌
LIANG Shuang;LIU Peng-fei;CHENG Xue-ming;ZHANG Meng-di;LI Bin;YANG Hui-bin(State Key Laboratory of the Discovery and Development of Novel Pesticide,Shenyang Sinochem Agrochemicals R&D Co.,Ltd.,Shenyang 110021,China)
出处
《农药》
CAS
CSCD
北大核心
2021年第7期475-477,495,共4页
Agrochemicals
基金
“十三五”国家重点研发计划项目(2016YFD0300708)。
关键词
芳氧苯氧丙酸
合成
除草活性
aryloxyphenoxypropionic acid
synthesis
herbicidal activity
