摘要
肝性脑病(HE)在很大程度上增加了肝病患者的经济负担,严重影响了患者的生活质量。HE病理基础复杂且影响因素繁多,发病机理尚未完全明晰。其临床治疗尚无特异有效的方法,药物治疗临床疗效欠佳,许多药物耐受性差、依从性低,不良反应普遍。就HE的蛋白质类食物和调节肠道菌群的药物治疗途径进行分析与归纳,以期为HE临床治疗提供新思路及优质方案。
Hepatic encephalopathy(HE)greatly increases the economic burden of patients with liver disease and seriously affects their quality of life.HE has a complex pathological basis and various influencing factors,and its pathogenesis has not been fully clarified.There is still no specific effective therapy for this disease,and drug therapy often has an unsatisfactory clinical effect,as many drugs have poor tolerability,low compliance,and common adverse effects.This article analyzes and summarizes the non-drug therapies for hepatic encephalopathy including protein food and gut microbiota regulation,in order to provide new ideas and high-quality regimens for clinical treatment.
作者
乐滢玉
张荣臻
肖伟松
覃小宾
曾胜澜
毛德文
LE Yingyu;ZHANG Rongzhen;XIAO Weisong;QIN Xiaobin;ZENG Shenglan;MAO Dewen(Graduate School of Guangxi University of Chinese Medicine,Nanning 530222,China;First Department of Hepatology,The First Affiliated Hospital of Guangxi University of Chinese Medicine,Nanning 530023,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2021年第7期1694-1698,共5页
Journal of Clinical Hepatology
基金
国家自然科学基金面上项目(81774236)
国家自然科学基金项目(81960841)
广西自然科学基金课题(2018GXNSFAA281096)
广西科技计划项目-广西科技基地和人才专项(桂科AD17129001)
广西研究生教育创新计划资助项目(YCXJ2021038)。
关键词
肝性脑病
胃肠道微生物组
健康膳食
治疗学
Hepatic Encephalopathy
Gastrointestinal Microbiome
Healthy Diet
Therapeutics
