摘要
目的探讨经直肠超声造影成像联合磁共振对前列腺癌的早期诊断价值。方法回顾性分析我院2017年3月至2019年7月收治的疑似前列腺癌的78例患者临床资料,所有患者均行经直肠超声造影(CEUS)和磁共振(MRI)检查,以前列腺穿刺活检结果为“金标准”。比较单独CEUS、单独MRI以及CEUS联合MRI检查对前列腺癌的早期诊断价值。结果78例患者经活检确诊31例前列腺癌,前列腺良性增生47例;CEUS、MRI以及CEUS联合MRI对诊断前列腺癌的敏感度分别为74.19%、77.42%、89.74%,准确度分别为76.92%、79.49%、89.74%,特异度分别为78.72%、80.85%、89.36%;CEUS诊断前列腺癌AUC为0.765,MRI诊断前列腺癌AUC为0.791,CEUS联合MRI诊断前列腺癌AUC为0.898,CEUS联合MRI诊断前列腺癌的ROC曲线面积显著大于MRI或CEUS(P<0.05)。结论MRI联合CEUS相较单独采用一种检查方法诊断前列腺癌,可有效提高诊断效能,提高前列腺癌检出率,为前列腺癌早期诊治提供有力帮助。
Objective To investigate the early diagnostic value of transrectal contrast-enhanced ultrasound(CEUS)combined with magnetic resonance imaging(MRI)in prostate cancer.Methods The clinical data of 78 patients with suspected prostate cancer admitted to our hospital from March 2017 to July 2019 were retrospectively analyzed.All patients underwent CEUS and MRI examinations,then the early diagnostic value of different methods were compared based on the tissue biopsy results.Results Biopsy results showed that there were 31 cases of prostate cancer and 47 cases of benign prostatic hyperplasia.The sensitivity of CEUS,MRI and CEUS combined MRI in the diagnosis of prostate cancer were 74.19%,77.42%,89.74%,the accuracy of the three methods were 76.92%,79.49%,89.74%,and the specificity of the three methods were 78.72%,80.85%,and 89.36%,respectively.The area under the ROC curve(AUC)of CEUS combined with MRI in diagnosising prostate cancer was significantly larger than that of MR or CEUS(0.898 vs 0.791&0.765,P<0.05).Conclusion Compared with the single detection,combined detection of MRI and CEUS can effectively improve the diagnostic efficiency and detection rate of prostate cancer,and provide basis for early diagnosis and treatment.
作者
赵云歆
孙剑
王晓莲
蔡秋琼
康慧莉
李文敏
黄海栋
江怡
ZHAO Yun-xin;SUN Jian;WANG Xiao-lian;CAI Qiu-qiong;KANG Hui-li;LI Wen-min;HUANG Hai-dong;JIANG Yi(Department of Ultrasound,Shanghai Pudong New Area Punan hospital,Shanghai 200125,China;Department of Urology,Shanghai Pudong New Area Punan hospital,Shanghai 200125,China;Department of Radiology,Shanghai Pudong New Area Punan hospital,Shanghai 200125,China)
出处
《中国CT和MRI杂志》
2021年第8期120-122,128,共4页
Chinese Journal of CT and MRI
基金
上海市浦东新区科技发展基金(PKJ2016-Y04)
上海市浦东新区科技发展基金(PKJ2015-Y48)。
关键词
超声造影
磁共振
前列腺癌
诊断价值
Contrast-enhanced Ultrasound
Magnetic Resonance
Prostate Cancer
Diagnostic Value