摘要
目的分析Xp11.2易位/TFE3基因融合相关性肾癌(简称Xp11.2易位性肾癌)的MRI表现及特征。方法选取经手术病理证实的6例Xp11.2易位性肾癌患者资料,所有患者术前均行MRI检查,对肿瘤MRI特征进行分析。结果6例患者中5例年龄在25~38岁;6例T2WI均表现为不均匀低信号,2例表现为T1WI等信号;6例DWI信号均明显高于肾实质,ADC图病灶呈明显低信号;6例同反相位均未见脂质成分;1例无出血,5例不同程度出血;5例表现为中度强化,1例表现为明显强化,6例延迟期均廓清;6例均有假包膜,其中3例假包膜不完整,肾周癌灶形成或肾盂及输尿管受累。结论Xp11.2易位性肾癌具有一定的MRI信号特点,增强对该病的认识,有助于提高术前诊断的正确率。
Objective To analyze the imaging findings and imaging characteristics analysis of renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions(abbreviation as Xp11.2 translocation renal cell carcinoma).Methods A retrospective analysis of 6 cases of Xp11.2 translocation renal cell carcinoma confirmed by operation and pathology was performed.All patients underwent MRI before operation.The MRI features of the tumor were analyzed.Results Among the 6 patients,5 cases were between 25 and 38 years old;T2WI signals of 6 cases were nonuniform low signals;T1WI signals of 2 cases were equal to the renal cortex;DWI signals of 6 cases were significantly higher than the renal parenchyma,and the ADC signals were significantly reduced;lipid signal of 6 cases was not observed in out phase and in phase;1 cases had no hemorrhage,5 cases had a different degree hemorrhage;5 cases showed moderate enhancement,1 case showed obvious enhancement,6 cases were washed out;6 cases had capsules,3 cases had incomplete capsule,with perirenal cancer formation or renal pelvis and ureteral involvement.Conclusion Renal cell carcinoma associated with Xp11.2 translocation/TFE3 gene fusions has certain MRI signal characteristics,and improving the understanding of the disease will help to improve the preoperative diagnosis rate.
作者
李小龙
史立新
杜其聪
王巍
邵立伟
王英伟
LI Xiaolong;SHI Lixin;DU Qicong;WANG Wei;SHAO Liwei;WANG Yingwei(Department of Diagnostic Radiology, The First Medical Center of PLA General Hospital, Beijing 100853, P.R.China;Department of Urology, The First Medical Center of PLA General Hospital, Beijing 100853, P.R.China;Department of Pathology, The First Medical Center of PLA General Hospital, Beijing 100853, P.R.China)
出处
《医学影像学杂志》
2021年第6期1022-1025,共4页
Journal of Medical Imaging
关键词
肾癌
基因融合
磁共振成像
Renal cell carcinoma
Fusion gene
Magnetic resonance imaging
