摘要
IgA肾病发病机制复杂,尚未完全了解。一些microRNA(miRNA)在IgA肾病患者中出现差异性的表达,提示可能参与IgA肾病的发病机制,作为新的非创伤性生物标志物,miRNA为诊断、预防以及改善IgA肾病预后提供了新的研究方向。
The pathogenesis of Ig A nephropathy is complex and has not been fully understood.Some micro RNAs(mi RNAs)are differentially expressed in patients with Ig A nephropathy,suggesting that mi RNA may be involved in the pathogenesis of Ig A nephropathy.As a new non-invasive biomarker,mi RNA provides a new research direction for the diagnosis,prevention and improvement of the prognosis of Ig A nephropathy.This paper reviews the literatures about the relationship between Ig A nephropathy and some mi RNAs at home and abroad.
作者
兰竞超(综述)
沈颖(审校)
LAN Jingchao;SHEN Ying(Department of Nephrology,Beijing Children’s Hospital,Capital Medical University,Beijing 100045;Beijing Key Laboratory of Chronic Kidney Disease and Blood Purification in Childhood,Beijing Children’s Hospital,Capital Medical University,Beijing 100045;Key Laboratory of Major Diseases in Children,Ministry of Education,Beijing Children’s Hospital,Capital Medical University,Beijing 100045,China)
出处
《临床与病理杂志》
CAS
2021年第6期1395-1398,共4页
Journal of Clinical and Pathological Research
基金
国家自然科学基金(81600551)。
