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心气虚血瘀证动物模型的构建与评价 被引量:5

Construction and evaluation of an animal model of heart qi deficiency and blood stasis syndrome
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摘要 中医证候模型起步较晚,为推动中医现代化的发展,要求深入研究和探讨中医证候动物模型。气虚血瘀证作为心血管疾病常见的证型,其动物模型的建立是中医证候实验研究的热点问题,通过对各种心气虚血瘀证动物模型造模方法进行研究,观察实验动物的宏观体征、超声心动图、血流动力学等指标,客观评价其造模方法,同时提出当前中医证候动物模型研究中存在的问题,并对其进行了展望,为今后探究心气虚血瘀证的临床治疗提供模型支持。 Traditional Chinese medicine(TCM)syndrome models have only recently been explored.To promote the modernization of TCM,in-depth research,and discussion of TCM syndrome,animal models are required.As a common syndrome type of cardiovascular disease,the establishment of an animal model of qi deficiency and blood stasis syndrome is a hot issue in the experimental study of TCM syndrome.Through research on various animal models of heart qi deficiency and blood stasis syndrome,the macroscopic signs,echocardiography,hemodynamics,and other indicators of experimental animals were observed,and the modeling method were objective ly evaluated.At the same time,the current animal model of TCM syndrome was proposed.The existing problems in the study and prospects of heart qi deficiency and blood stasis syndrome clinical treatment could be addressed by the development of new models.
作者 王云姣 张婉勤 张军平 吕仕超 WANG Yunjiao;ZHANG Wanqin;ZHANG Junping;LYU Shichao(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300193,China)
出处 《中国实验动物学报》 CAS CSCD 北大核心 2021年第3期405-412,共8页 Acta Laboratorium Animalis Scientia Sinica
基金 天津市卫生计生行业高层次人才选拔培养工程,中华中医药学会青年人才托举工程(CACM-2018-QNRC2-B04)。
关键词 心血管疾病 气虚血瘀证 动物模型 模型评价 cardiovascular diseases qi deficiency and blood stasis animal model model evaluation
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