摘要
目的:探究中药雾化吸入结合保留灌肠治疗多重耐药菌(Multi Drug Resistant Organism,MDRO)感染所致高热病的临床疗效。方法:随机选取2019年7月-2020年3月济宁市中医院收治的36例MDRO所致高热病患者,随机分为观察组和对照组,每组各18例,对照组进行常规西药治疗,观察组在对照组基础上进行中药雾化吸入结合保留灌肠治疗。观察记录患者的中医证候积分、细菌学疗效、高敏C反应蛋白(High-sensitivity C-reactive Protein,hs-CRP)、白细胞计数(White Blood Count,WBC)以及降钙素原(Procalcitonin,PCT)等指标。结果:治疗后,观察组患者主症、次症证候积分均显著低于对照组,差异显著(P<0.05);观察组的细菌清除率指标优于对照组,P<0.05。两组患者治疗后WBC、hs-CRP、PCT都降低,与治疗前差异显著(P<0.05);观察组的WBC、hs-CRP、PCT等指标优于对照组,P<0.05。结论:中药雾化吸入结合保留灌肠治疗MDRO所致高热病的临床效果显著,能够有效地改善临床症状,更好地清除细菌,提高用药的临床安全性。
Objective:To explore the clinical efficacy of TCM medicine atomized inhalation plus retention enema on high fever caused by MDRO infection.Methods:36 cases were randomly divided into the observation group and the control group,18 cases in each.The control group received conventional western medicine,and the observation group took TCM medicine atomized inhalation plus retention enema more.Results:After treatment,the scores of the primary and secondary syndromes in the observation group were significantly lower than those in the control group,with significant differences(P<0.05).The bacterial clearance in the observation group was better than the control group,P<0.05.After treatment,the WBC,hs-CRP,and PCT levels in the groups were all decreased,with significant differences compared with before treatment(P<0.05).The WBC,hs-CRP,PCT and other indicators in the observation group were better than the control group,P<0.05.Conclusion:TCM medicine atomized inhalation plus retention enema shows a significantly clinical effect on high fever caused by MDRO,which can effectively ameliorate the clinical symptoms of patients,eliminate bacteria,and improve the clinical safety of medication.
出处
《中医临床研究》
2021年第10期102-104,共3页
Clinical Journal Of Chinese Medicine
关键词
中药雾化
中药灌肠
多重耐药菌所致高热病
细菌学疗效
TCM medicine atomization
TCM medicine enema
High fever caused by MDRO infection
Bacteriological effects
