摘要
目的运用中医传承辅助平台挖掘中医药治疗眩晕的用药规律。方法检索中国知网2015年5月—2020年5月运用中医药治疗眩晕的相关文献,以“眩晕”或“头晕”且“中医”或“中医药”为主题进行高级检索,筛选处方构建数据库,分析处方中药物和药对使用频次及药物间的关联规则、处方规律等。结果最终纳入处方234首,涉及235味中药,分析得出高频次药物有白术、茯苓、天麻、川芎、当归等;应用较多的中药类别是补虚药、利水渗湿药、平肝息风药、活血化瘀药等;在药性方面,四气以温、寒为主,五味以甘、辛为主,而归经以肝、脾经用药为主;高频药物组合有“白术、茯苓”“白术、天麻”“茯苓、天麻”等;药物间的关联规则中,“陈皮->白术”的关联性最强;并挖掘出核心组合12个,新处方6首。结论通过挖掘及分析得出治疗眩晕以理气活血、燥湿化痰、平抑肝阳、补益气血、滋阴补肾为主,符合中医标本兼治原则,其核心组合与新处方可为临床用药和新药研发提供参考。
Objective To explore the medication rules of traditional Chinese medicine in the treatment of vertigo by using traditional Chinese medicine inheritance auxiliary platform.Methods The related literatures on the treatment of vertigo with traditional Chinese medicine from May 2015 to May 2020 in CNKI were searched.The theme with“vertigo”or“dizziness”and“Chinese medicine”or“traditional Chinese medicine”was advanced searched.The prescription was screened and the database was built.The frequency of drug use and drug pairs use,association rules and prescription rules were analyzed.Results Finally,234 prescriptions were included,involved 235 kinds of traditional Chinese medicine,and the high-frequency drugs were Atractylodis Macrocephalae Rhizoma,Poria,Gastrodiae Rhizoma,Chuanxiong Rhizoma and Angelicae Sinensis Radix.The most commonly used traditional Chinese medicines were tonifying deficiency drugs,diuretic drugs,calming liver and calming wind drugs,promoting blood circulation and removing blood stasis drugs,etc.In terms of drug properties,the four qi was mainly warm and cold,the five flavors was mainly sweet and pungent,and the meridian tropism was mainly liver and spleen meridians.High frequency drug combinations included“Atractylodis Macrocephalae Rhizoma and Poria”“Atractylodis Macrocephalae Rhizoma and Gastrodiae Rhizoma”“Poria and Gastrodiae Rhizoma”,etc.Among the association rules between drugs,“Citri Reticulatae Pericarpium->Atractylodis Macrocephalae Rhizoma”had the strongest association.Twelve core combinations and six new prescriptions were found.Conclusion Through excavation and analysis,it is concluded that the treatment of vertigo mainly includes regulating qi and activating blood circulation,drying dampness and resolving phlegm,calming liver yang,tonifying qi and blood,nourishing yin and kidney,which is in line with the principle of treating both symptoms and signs of traditional Chinese medicine.Its core combination and new prescription can provide reference for clinical
作者
林玲
袁捷
刘冬玲
韩祖成
骆凡
王莹
陈杰
LIN Ling;YUAN Jie;LIU Dongling;HAN Zucheng;LUO Fan;WANG Ying;CHEN Jie(The First Clinical College,Shaanxi University of Chinese Medicine,Shaanxi Province,Xianyang 712046,China;Department of Encephalopathy,Shaanxi Traditional Chinese Medicine Hospital,Shaanxi Province,Xi’an 710003,China)
出处
《中国医药导报》
CAS
2021年第18期146-150,共5页
China Medical Herald
基金
国家中医药管理局中医药行业科研专项项目(201507001-05)。
关键词
中医药
眩晕
用药规律
中医传承辅助平台
Traditional Chinese medicine
Vertigo
Medication rule
Traditional Chinese medicine inheritance auxiliary platform
