摘要
目的观察闭合复位空心螺钉内固定法结合富血小板血浆治疗中青年股骨颈骨折的临床疗效。方法回顾性分析海口市第三人民医院及上海市第六人民医院于2015年1月至2018年1月收治的80例中青年股骨颈骨折患者资料,根据治疗方法不同将其分为2组,对照组(n=40)给予闭合复位空心螺钉内固定治疗,联合组(n=40)予以闭合复位空心螺钉内固定联合富血小板血浆(PRP)治疗。对比2组骨折愈合与完全负重时间以及手术时间及术中出血量,比较2组术后1周、6周、3个月、6个月及12个月髋关节功能Harris评分、骨折愈合情况(Fernandez-Esteve骨痂评分),观察比较2组骨不连与股骨头坏死发生率。结果2组患者手术时间、术中出血量比较,差异均无统计学意义(P>0.05);联合组完全负重时间及骨折愈合时间显著短于对照组,差异有统计学意义(P<0.05);联合组患者术后1周、6周、3个月、6个月、12个月的Harris评分均高于对照组,差异均有统计学意义(P<0.05);联合组患者术后6周、3个月、6个月及12个月的Fernandez-Esteve骨痂评分均高于对照组,差异均有统计学意义(P<0.05);联合组患者的骨不连发生率、股骨头坏死发生率均明显低于对照组,差异均有统计学意义(P<0.05)。结论与单纯闭合复位空心螺钉内固定治疗相比,闭合复位空心螺钉内固定联合富血小板血浆治疗股骨颈骨折,能够明显缩短患者完全负重时间与骨折愈合时间,降低股骨头坏死与骨不连发生率,改善患者的髋关节功能。
Objective To observe the effect of closed reduction and cannulated screw internal fixation combined with platelet rich plasma(PRP)in the treatment of femoral neck fracture in young and middle-aged adults.Methods The data of 80 middle-aged and young patients with femoral neck fracture admitted to The Third People's Hospital of Haikou and The Sixth People's Hospital of Shanghai from January 2015 to January 2018 were retrospectively analyzed,according to different treatment they were divided into two groups,control group(n=40)received closed reduction and hollow screw internal fixation treatment,combined group(n=40)received closed reduction hollow screw internal fixation with platelet rich plasma(PRP)therapy,compare two groups of patients with surgery index(full weight-bearing time,operation time,intraoperative blood loss,fracture healing time).The Harris score of hip joint function and fracture healing(Fernandez-Esteve bone crub score)were compared between the two groups at 1 week,6 weeks,3 months,6 months and 12 months after surgery.The incidence of nonunion and necrosis of femoral head were observed and compared between the two groups.Results There were no significant differences in operative time and intraoperative blood loss between the two groups(P>0.05).The fracture healing time and full weight bearing time in the combined group were significantly shorter than those in the control group,with statistical significance(P<0.05).Harris scores at 6 weeks,3 months,6 months and 12 months after surgery in combined group were higher than those in control group,and the difference was statistically significant(P<0.05).The Fernandez-Esteve callus scores at 6 weeks,3 months,6 months and 12 months after surgery in the combined group were higher than those in the control group,and the difference was statistically significant(P<0.05).The incidence of bone nonunion and necrosis of femoral head in combined group were lower than those in control group,with statistical significance(P<0.05).Conclusion In the treatment of femoral n
作者
王斌
邓高鹏
林正坚
侯平
汪春阳
柴益民
WANG Bin;DENG Gao-peng;LIN Zheng-jian(Department of Orthopedics,The Third People's Hospital of Haikou,Haikou Hainan 571100,China)
出处
《临床和实验医学杂志》
2021年第12期1287-1290,共4页
Journal of Clinical and Experimental Medicine
基金
海南省自然科学基金项目(编号:819MS141)。
关键词
中青年
股骨颈骨折
闭合复位空心螺钉内固定
富血小板血浆
骨折愈合
髋关节功能
Young and middle-aged
Femoral neck fracture
Closed reduction cannulated screw internal fixation
Platelet rich plasma fracture
Healing hip joint function