摘要
目的分析肌骨超声半定量评分与类风湿关节炎(RA)血清学指标C-反应蛋白(CRP)、免疫球蛋白A(IgA)及病情活动度的相关性。方法选取我院收治的RA患者90例,根据28处关节疾病活动度评分分为缓解期组19例、低活动期组25例、中活动期组28例、高活动期组18例,比较各组患者肌骨超声半定量分级评分、CRP、IgA及病情活动度的差异,并行相关性分析。结果各组患者滑膜增生、血流信号、骨侵蚀、关节积液半定量分级评分及总评分比较差异均有统计学意义(均P<0.05);各组患者血清CRP、IgA及病情活动度比较差异均有统计学意义(均P<0.05)。相关性分析显示,滑膜增生、血流信号、骨侵蚀、关节积液半定量分级评分及总评分与CRP、IgA均呈正相关,与病情活动度呈负相关(均P<0.05)。结论肌骨超声半定量评分与RA患者血清CRP、IgA及病情活动度均相关。
Objective To analyze the correlation between musculoskeletal ultrasound semi-quantitative score and rheumatoid arthritis(RA)serum indexes C-reactive protein(CRP),immunoglobulin A(IgA)and disease activity.Methods Ninety patients with RA admitted to our hospital were selected,according to the scores of rheumatoid arthritis activity(DSA28),the patients were divided into remission group(n=19),low activity group(n=25),moderate activity group(n=18)and high activity group(n=18).The semi-quantitative grading score,serum CRP,IgA and disease activity were compared among the four groups,and the correlation was analyzed.Results There were significant differences among the 4 groups in semiquantitative score of synovial hyperplasia,blood flow signal,bone erosion,joint effusion,and total score(all P<0.05),there were significant differences in serum CRP,serum IgA,and disease activity among the groups(all P<0.05).Correlation analysis showed that the semi-quantitative score of synovial hyperplasia,blood flow signal,bone erosion,joint effusion,and total score were positively correlated with CRP and IgA,and negatively correlated with disease activity(all P<0.05).Conclusion The musculoskeletal ultrasound semi-quantitative score is correlated with serum CRP,IgA and disease activity in RA patients.
作者
邵琦
王晨达
贾丛丛
孙一红
张林华
谭亚敏
SHAO Qi;WANG Chenda;JIA Congcong;SUN Yihong;ZHANG Linhua;TAN Yamin(Department of Ultrasound,Ningbo Hospital of Traditional Chinese Medicine,Zhejiang 315000,China)
出处
《临床超声医学杂志》
CSCD
2021年第6期471-474,共4页
Journal of Clinical Ultrasound in Medicine
关键词
超声检查
肌骨
类风湿关节炎
血清学指标
病情活动度
相关性
Ultrasonography,musculoskeletal
Rheumatoid arthritis
Serological indicators
Disease activity
Correlation
