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针灸结合康复对脑卒中偏瘫疗效及血清NPY、Hcy水平和神经功能的影响 被引量:14

Efficacy of Acu-moxibustion Combined with Rehabilitation for Stroke Hemiplegia and Its Influence on Levels of Serum NPY and Hcy and Neurological Function
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摘要 目的:观察针灸结合康复训练治疗脑卒中偏瘫效果及对患者血清神经肽Y(NPY)、同型半胱氨酸(Hcy)水平、神经功能、运动功能及日常生活能力影响。方法:纳入2017年6月~2019年6月120例脑卒中偏瘫住院患者,按住院顺序奇偶数法分成观察组、对照组各60例,观察组在常规对症支持治疗基础上,给予针刺、艾灸治疗联合康复训练,对照组仅接受康复训练,连续观察8周,比较两组治疗前后血清NPY、Hcy水平变化,采用美国国立卫生院研究所卒中量表(NIHSS)评价患者神经功能,运动功能Fugl-Meyer评分(FMA)评价运动功能,改良Barthel指数(MBI)评价日常生活能力,并评价两组治疗效果。结果:治疗前,两组血清NPY、Hcy水平、NIHSS、FMA及MBI评分比较差异无统计学意义(P>0.05),治疗8周后,两组血清NPY、Hcy水平均显著低于治疗前(P<0.05),NIHSS评分显著低于治疗前(P<0.05),FMA及MBI评分显著高于治疗前(P<0.05),且观察组上述指标降低或升高幅度大于对照组(P<0.05);治疗8周后,观察组总有效率91.67%,高于对照组的76.67%(P<0.05)。结论:对脑卒中偏瘫患者采取针灸结合康复治疗,较单纯康复治疗可更好下调血清NPY、Hcy水平,改善神经功能缺损,提高患者运动能力及日常生活能力,临床疗效更佳。 Objective: To analyze the effect of acu-moxibustion combined with rehabilitation training for stroke hemiplegia and its influence on levels of serum neuropeptide Y(NPY) and homocysteine(Hcy), neurological function, motor function and daily living ability. Methods: A total of 120 hospitalized patients with stroke hemiplegia from June 2017 to June 2019 were enrolled and divided into an observation group and a controlled group according to the odevity of hospitalization sequence, with 60 cases in each group. The observation group was given acu-moxibustion combined with rehabilitation training on the basis of conventional symptomatic supportive treatment, and the controlled group was only given rehabilitation training, and they were given 8 weeks of continuous observation. The changes of serum NPY and Hcy levels were compared between the two groups before and after treatment, and the National Institutes of Health Stroke Scale(NIHSS) was used to evaluate the neurological function of patients, and the motor function Fugl-Meyer assessment score(FMA) was used to evaluate the motor function, and the modified Barthel index(MBI) was used to assess the daily living ability, and the treatment effects were evaluated in the two groups. Results: Before treatment, there were no significant differences in the levels of serum NPY and Hcy and scores of NIHSS, FMA and MBI between the two groups(P > 0.05). After 8 weeks of treatment, the levels of serum NPY and Hcy in the two groups were significantly lower than those before treatment(P < 0.05), and the NIHSS score was significantly lower than that before treatment(P < 0.05) while the scores of FMA and MBI were significantly higher than those before treatment(P < 0.05), and the decreases or increases of above-mentioned indicators in the observation group were greater than those in the controlled group(P < 0.05). After 8 weeks of treatment, the total effective rate in the observation group was higher than that in the controlled group(91.67% vs 76.67%)(P < 0.05). Conclusion: Compared wi
作者 罗欢欢 李娜 吴丹 袁道玉 张建琴 王小利 LUO Huanhuan;LI Na;WU Dan(Department of Rehabilitation,West China Guang’an Hospital of Sichuan University,Guang’an Sichuan 638500,China)
出处 《四川中医》 2021年第5期182-186,共5页 Journal of Sichuan of Traditional Chinese Medicine
关键词 脑卒中偏瘫 针灸 康复训练 神经功能 神经肽Y 同型半胱氨酸 Stroke hemiplegia Acu-moxibustion Rehabilitation training Neurological function Neuropeptide Y Homocysteine
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