摘要
目的了解降钙素原(PCT)、C反应蛋白(CRP)和D-二聚体(DD)在重症肺炎患者中的表达及其与预后的关系。方法选取重症肺炎患者82例,根据预后不同分为好转组和预后不良组。比较两组患者的CRP、PCT及DD的表达水平及其与预后的关系。结果好转组患者的血清CRP、PCT的初始值和最大值以及DD最大值均显著低于预后不良组(P<0.01);CRP、PCT及DD上升比例亦明显低于预后不良组(P<0.01)。结论血清CRP、PCT、DD对重症肺炎患者的预后有较高的预测价值。
Objective To investigate the expression of procalcitonin(PCT),C-reactive protein(CRP)and D-dimer(DD)levels in the patients with severe pneumonia and its relevance to the prognosis.Methods A total of 82 patients with severe pneumonia were selected and divided into the Improvement Group and Poor Prognosis Group.The two groups were compared in terms of the expressions ofPCT,CRP and D-dimer levels and their relevance to the prognosis.Results The initial and maximum value of serum CRP and PCT levels and the maximum value of DD in the Improvement Group were significantly lower than those in the Poor Prognosis Group(P<0.05);The increases in serum CRP,PCT and DD in the Improvement Group were significantly lower than those in the Poor Prognosis Group(P<0.01).The area under curve(AUC),specificity and sensitivity of serum CRP,PCT,DD and the combined indicators in the assessment of severe pneumonia were significantly higher than single indicators(P<0.01).Conclusion Serum CRP,PCT,and DD have great value in the prediction of prognosis of patients with severe pneumonia.
作者
杨少芬
李素
YANG Shao-fen;LI Su(The Second Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,China)
出处
《广东医科大学学报》
2021年第3期284-286,共3页
Journal of Guangdong Medical University
