摘要
目的分析阻塞性睡眠呼吸暂停综合征(obstructive sleep apnea syndrome,OSAS)与心脏手术患者术后发生痛觉过敏的关系。方法选择2016年5月至2020年8月间接受心脏瓣膜手术治疗的124例患者作为研究对象。术后用数字疼痛量表评价是否发生痛觉过敏。根据是否发生痛觉过敏将124例患者分为2组:痛觉过敏组(n=32)和非痛觉过敏组(n=92)。Logistic回归分析OSAS与痛觉过敏的关系。结果痛觉过敏组的吸烟史占比、咪达唑仑使用史占比和OSAS史占比均高于非痛觉过敏组,差异均有统计学意义(P<0.05)。Logistic回归分析结果显示吸烟史、咪达唑仑使用史和OSAS史均是术后痛觉过敏的独立危险因素(P<0.05)。平均每小时睡眠发生呼吸暂停和低通气次数(AHI)与数字疼痛量表评分呈正相关关系(rs=0.379,P<0.001)。结论OSAS与心脏手术患者术后痛觉过敏有关。
Objective To analyze the relationship between obstructive sleep apnea syndrome(OSAS)and postoperative hyperalgesia in patients undergoing cardiac operation.Methods 124 patients who received cardiac valve operation from May 2016 to August 2020 were selected as study subjects.The digital pain scale was used to evaluate whether hyperalgesia occurred after operation.According to the occurrence of hyperalgesia,124 patients were divided into 2 groups:hyperalgesia group(n=32)and non-hyperalgesia group(n=92).Logistic regression was used to analyze the relationship between OSAS and hyperalgesia.Results The percentages of smoking history,midazolam and OSAS in the hyperalgesia group were higher than those in the non-hyperalgesia group,and the differences were statistically significant(P<0.05).Logistic regression analysis showed that smoking history,midazolam and OSAS history were all independent risk factors for postoperative hyperalgesia(P<0.05).The average per hour of apnea-hypopnea index(AHI)was positively correlated with the score of the digital pain scale(r=0.379,P<0.001).Conclusion OSAS is related to postoperative hyperalgesia in patients undergoing cardiac surgery.
作者
李庆丰
LI Qing-feng(Department of Anesthesiology, The second People's Hospital of Nanyang, Nanyang 473000, China)
出处
《牡丹江医学院学报》
2021年第3期61-63,82,共4页
Journal of Mudanjiang Medical University
