摘要
心脏再同步化治疗通常通过双心室起搏实现,但因解剖因素等导致的左心室电极无法成功植入以及植入后较高的无应答率限制了双心室起搏的应用。希氏束起搏(HBP)不仅符合心脏电生理,还能实现心脏再同步化。HBP不仅在伴左束支传导阻滞的左心室功能受损的心力衰竭治疗中具有良好的疗效,还可替代双心室起搏,使伴有完全性右束支传导阻滞、非特异室内传导阻滞、双心室起搏无应答心力衰竭患者达到双心室起搏无法达到的临床及心脏超声获益。
Cardiac resynchronization therapy is usually achieved by biventricular pacing,but the application is limited by the failure of implantation of left ventricular leads due to anatomical factors and the high non-response rate after implantation.His-bundle pacing(HBP)not only conforms to the physiological structure of the heart,but also realizes cardiac resynchronization.HBP not only has a good effect in the treatment of heart failure with impaired left ventricular function accompanied by left bundle branch block,but also can replace biventricular pacing,so that the patients with complete right bundle branch block,nonspecific ventricular block and biventricular pacing nonresponsive heart failure can achieve the clinical and echocardiographic benefits that biventricular pacing cannot realize.
作者
李明阳
王沛坚
LI Mingyang;WANG Peijian(Department of Cardiology,the First Affiliated Hospital of Chengdu Medical College/Key Laboratory of Aging and Vascular Homeostasis,Sichuan Provincial Universities,Chengdu 610500,China)
出处
《医学综述》
CAS
2021年第11期2157-2162,共6页
Medical Recapitulate
基金
国家自然科学基金(81970262)
成都医学院第一附属医院专项科学研究基金(CYFY2020YB07)。