摘要
针刺镇痛在国内外应用广泛且效果显著,目前较明确的镇痛机制是针刺通过抑制疼痛上行传导或促进下行抑制系统以快速镇痛。笔者团队之前的研究表明反复针刺后的抗炎镇痛效应出现,由此推测炎症可能是导致疼痛的根本原因。通过文献分析,笔者发现炎症在疼痛的外周敏感化和中枢敏感化中发挥重要作用,认为针刺通过控制外周和中枢炎症可有效抑制疼痛,可能是针刺镇痛的根本。因此,针刺抗炎镇痛的机制有待进一步系统研究,将为疼痛的炎症靶点治疗提供理论基础。
Acupuncture analgesia is widely used home and abroad,and its effect is significant.At present,the more clear mechanism of acupuncture analgesia is that it can quickly relieve pain by inhibiting pain upward conduction or promoting downward inhibition system.Early researches showed that acupuncture has anti-inflammatory and analgesic effects after repeated needling,so it is speculated that inflammation may be the root cause of pain.It is found that inflammation plays an important role in the peripheral and central sensitization of pain by analyzing the literature.It is suggested that acupuncture can inhibit pain effectively by controlling peripheral and central inflammation,which may be the basis of acupuncture analgesia.Therefore,the anti-inflammatory and analgesic mechanism of acupuncture needs to be further studied,which will provide theoretical basis for the treatment of inflammatory target of pain.
作者
鲁珊珊
王佳琦
黄锦
李姗姗
赵亚丹
王松涛
秦思茹
李威
唐慧玲
郭义
徐枝芳
LU Shanshan;WANG Jiaqi;HUANG Jin;LI Shanshan;ZHAO Yadan;WANG Songtao;QIN Siru;LI Wei;TANG Huiling;GUO Yi;XU Zhifang(Research Center of Experimental Acupuncture Science, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China;National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin 300381, China)
出处
《针灸临床杂志》
2021年第5期1-4,共4页
Journal of Clinical Acupuncture and Moxibustion
基金
国家自然科学基金面上项目,编号:81873369
国家自然科学基金青年项目,编号:81704146。
关键词
针刺
抗炎
镇痛
外周敏化
中枢敏化
Acupuncture
Anti-inflammation
Analgesia
Peripheral sensitization
Central sensitization
