摘要
目的了解丛状血管瘤的临床特点及病理特征,探讨丛状血管瘤的治疗进展。方法总结近5年本科室诊断的7例丛状血管瘤患者的临床资料,并在中国知网检索2000-2020年发表的"丛状血管瘤"相关中文文献,纳入资料完整的病例63例,分析其临床特点。结果共纳入70例丛状血管瘤,其中男29例,女41例,年龄2个月~64岁,皮损分布于躯干22例、四肢36例。其中2例使用他克莫司软膏成功治疗了丛状血管瘤,其他治疗方案包括手术切除、系统性糖皮质激素、脉冲激光以及随访观察等。结论诊断丛状血管瘤需结合临床表现及组织病理,局限性皮损首选手术切除。丛状血管瘤的药物治疗较困难,外用他克莫司软膏疗效明显,可进一步扩大治疗样本量,探究其有效性及安全性。
Objective To explore the clinical and pathological characteristics of tufted angioma(TA),and to discuss the progress in therapeutic options.Methods The clinical data of 70 patients with TA were analyzed,including seven patients diagnosed in our department in the past five years and 63 cases searched in"CNKI"in the past 20 years.Results Among 70 patients with TA in this group,there were 29 males and 41 females.The age of these patients ranged from two months to 64 years old.The lesions of 22 cases distributed on the trunk,and 36 cases on the extremities.Two cases of TA were treated successfully with tacrolimus ointment.Other treatment options in this group included surgical excision,systematic glucocorticoids,pulsed laser and follow-up observations.Conclusion The diagnosis of tufted angioma should be based on clinical manifestations and histopathology.Surgical removal is an effective therapy for TA patients.It is difficult to treat TA with drugs,but topical tacrolimus is effective.The safety and efficacy of tacrolimus ointment in TA demands further large-scale clinical trials.
作者
肖月
刘宏杰
李晓雪
郝丹
蒋献
XIAO Yue;LIU Hongjie;LI Xiaoxue;HAO Dan;JIANG Xian(Department of Dermatology and Venereology,West China Hospital of Sichuan University,Chengdu 610041,China)
出处
《中国皮肤性病学杂志》
CAS
CSCD
北大核心
2021年第6期632-637,共6页
The Chinese Journal of Dermatovenereology
基金
国家自然科学基金项目(81872535)。
关键词
丛状血管瘤
回顾性分析
他克莫司软膏
Tufted angioma
Retrospective analysis
Tacrolimus ointment
