摘要
目的:探讨功能失调性及器质性疾病异常子宫出血(AUB)治疗中体内脂质过氧化状态对治疗效果的影响。方法:应用分层随机抽样法,分别抽取接受常规治疗的功能失调性AUB患者(A组)、接受常规治疗联合维生素A、E治疗的功能失调性AUB患者(B组)、接受常规治疗的器质性疾病AUB患者(C组)及接受常规治疗联合维生素A、E治疗的器质性疾病AUB患者(D组),各32例。回顾性分析四组资料,对比A组与B组、C组与D组治疗效果、血常规及激素水平,分析治疗后血清维生素A、E与血常规及激素的相关性。结果:(1)B组治疗总有效率高于A组(P<0.05);B组治疗后RBC、Hb及PLT高于A组(P<0.05),E 2、FSH、LH及P低于A组(P<0.05)。(2)D组治疗总有效率高于C组(P<0.05);D组治疗后RBC、Hb及PLT高于C组(P<0.05),E 2、FSH、LH及P低于C组(P<0.05)。(3)功能性及器质性疾病AUB治疗后血清维生素A及E与RBC、Hb及PLT呈正相关(P<0.05),与E 2、FSH、LH及P呈相关(P<0.05)。结论:通过调节体内脂质过氧化状态可显著改善功能失调性及器质性疾病AUB的治疗效果,促进患者血常规及激素水平的改善。
Objective:To investigate the effect of lipid peroxidation status on the treatment of abnormal uterine bleeding(AUB)with dysfunctional and organic diseases.Method:using stratified random sampling method,respectively,to extract the function loss of tonal AUB treated with routine therapy(group A),treated with conventional treatment combined vitamin A,E,the function of tonal AUB patients(group B),the AUB organic disease treated with conventional treatment group(C)and treated with conventional treatment combined vitamin A,E AUB organic disease patients(group D),32 cases each.The data of the four groups were retrospectively analyzed to compare the treatment effect,blood routine and hormone levels between group A and group B,and between group C and group D,and to analyze the correlation between serum vitamin A and E and blood routine and hormone levels after treatment.Results:(1)The total effective rate of group B was higher than that of group A(P<0.05).After treatment,RBC,HB and PLT in group B were higher than those in group A(P<0.05),while E2,FSH,LH and P in group B were lower than those in group A(P<0.05).(2)The total effective rate of group D was higher than that of group C(P<0.05);After treatment,RBC,Hb and PLT in group D were higher than those in group C(P<0.05),while E2,FSH,LH and P were lower than those in group C(P<0.05).(3)Serum vitamins A and E were positively correlated with RBC,Hb and PLT after treatment of functional and organic diseases(P<0.05),and were correlated with E2,FSH,LH and P(P<0.05).Conclusion:By regulating lipid peroxidation status in vivo,the therapeutic effect of AUB can be significantly improved,and the improvement of blood routine and hormone levels in patients with dysfunctional and organic diseases can be promoted.
作者
朱惠贻
何玉玫
李苗
杨林
Zhu Huiyi(Dongguan Eighth People's Hospital,Dongguan 523000)
出处
《黑龙江医药》
CAS
2021年第3期521-524,共4页
Heilongjiang Medicine journal
基金
东莞市社会科技发展(一般)项目(项目编号:2018507150281441)。
