摘要
创伤后应激障碍指个体在遭受强烈的身体和精神创伤后出现行为和精神异常的一种疾病。其三大核心症状为创伤事件再体验、警觉性增高以及回避、麻木。本文对创伤后应激障碍(PTSD)的概况、流行病学、致病机制、生物标记物及其预警诊断、防治措施等方面的研究进行综述,并提出相关研究中存在的问题及未来的研究方向。
Post-traumatic stress disorder(PTSD)is a disease,which is caused by intense physical and mental trauma and eventually develops behavioral and mental abnormalities.The three key symptoms of PTSD are reexperience of traumatic events,increased alertness,and avoidance or numbness.This paper makes a comprehensive review of PTSD and its progress in epidemiology,pathogenic mechanism,biomarkers,predicting diagnosis and prevention measures.Further,the existing problems in current researches and the direction in the future are discussed.
作者
伍芳慧
刘媛
Wu Fanghui;Liu Yuan(State Key Laboratory of Trauma,Burns and Combined Injury,Department of Special War Wound,Research Institute of Surgery,Daping Hospital,Army Medical University,Chongqing 400042,China)
出处
《创伤外科杂志》
2021年第6期472-475,共4页
Journal of Traumatic Surgery
基金
国家自然科学基金面上项目(81772066)
军队青年培育项目资助(16QNP105)。
关键词
创伤后应激障碍
发病机制
早期诊断
治疗
post-traumatic stress disorder
pathogenesis
early diagnosis
treatment