摘要
藏花醛是一种单萜醛,是藏红花的主要挥发性成分之一,也是藏红花香气产生的主要原因,在食品、饮品中广泛应用。现代药理学研究证明藏花醛有着广泛的药理学活性,如心血管保护作用、抗炎、抗氧化、抗肿瘤等多种特性,这些药理作用主要基于其具有高度抑制机体内活性氧(ROS)的潜力。本文对藏花醛的主要来源、理化性质进行介绍,着重总结了近年来藏花醛的药理活性及作用机制的研究进展。
As one of the main volatile components of saffron and the source of saffron aroma,safranal is a kind of monoterpenoid aldehyde and is widely used in food and drinks.Safranal has a wide range of pharmacological activities,such as cardiovascular protective effect,anti-inflammation,anti-oxidation and anti-tumor activities.These pharmacological actions are mainly based on its high potential to inhibit the activity of reactive oxygen species(ROS)in the body.This study introduced the main sources,physical and chemical properties of safranal,and concluded the research progresses of pharmacological activity and mechanism of safranal in recent years.
作者
施靖
郝子慧
张一昕
白月
王红芳
SHI Jing;HAO Zihui;ZHANG Yixin;BAI Yue;WANG Hongfang(The Fourth Hospital of Hebei Medical University,Shijiazhuang 050011,China;Pharmacy School,Hebei University of Chinese Medicine,Shijiazhuang 050200,China;Hebei Higher Education Institute Applied Technology Research Center on TCM Formula Preparation,Shijiazhuang 050091,China)
出处
《中医药学报》
CAS
2021年第6期112-118,共7页
Acta Chinese Medicine and Pharmacology
基金
河北省中医药管理局项目(2019081)。
关键词
藏花醛
药理作用
作用机制
Safranal
Pharmacological action
Mechanism of action
