摘要
目的探究重度妊娠期高血压疾病患者采用低分子肝素联合硫酸镁治疗的临床效果。方法选择60例重度妊娠期高血压疾病患者,采用随机数字表法分为对照组与研究组,每组30例。对照组采用单一硫酸镁治疗,研究组采用低分子肝素联合硫酸镁治疗,比较两组患者血小板计数、红细胞压积、凝血酶原时间、收缩压、舒张压、血浆D-二聚体水平及临床疗效。结果研究组患者血小板计数、红细胞压积、凝血酶原时间指标均明显优于对照组,差异有统计学意义(P<0.05)。研究组患者收缩压、舒张压、血浆D-二聚体水平分别为(132.01±5.22)mmHg、(78.65±5.20)mmHg、(1.80±0.45)mg/L,对照组患者收缩压、舒张压、血浆D-二聚体水平分别为(140.63±5.98)mmHg、(86.65±5.84)mmHg、(2.42±0.44)mg/L,研究组患者收缩压、舒张压、血浆D-二聚体水平均明显低于对照组,差异有统计学意义(P<0.05)。研究组患者治疗总有效率为96.67%,显著高于对照组的73.33%,差异有统计学意义(P<0.05)。结论重度妊娠期高血压疾病患者采用低分子肝素联合硫酸镁治疗效果显著,可改善其血液状态,显控制血压平衡,具有临床应用价值。
Objective To explore the clinical effect of low molecular weight heparin combined with magnesium sulfate in the treatment of severe pregnancy-induced hypertension syndrome(PESH).Methods Sixty patients with severe preeclampsia were selected and divided into control group and study group by random number table method,with 30 cases in each group.The control group was treated with magnesium sulfate alone,and the study group was treated with low molecular weight heparin combined with magnesium sulfate.The platelet count,hematocellular volume,prothrombin time,systolic blood pressure,diastolic blood pressure,plasma D-dimer levels and clinical effi cacy of the two groups were compared.Results The indexes of platelet count,hematocrit and prothrombin time in the study group were significantly better than those in the control group,with statistical significance(P<0.05).Team in patients with systolic pressure,diastolic blood pressure,plasma D-dimer level(132.01±5.22)mmHg,respectively,(78.65±5.20)mmHg,(1.80±0.45 mg/L)and control group in patients with systolic pressure,diastolic blood pressure,plasma D-dimer level(140.63±5.98)mmHg,respectively,(86.65±5.84)mmHg,(2.42±0.44 mg/L),the team in patients with systolic blood pressure,diastolic blood pressure,plasma D-dimer level were significantly lower than the control group,the difference was statistically signifi cant(P<0.05).The total effective rate of the study group was 96.67%,which was signifi cantly higher than that of the control group(73.33%),the difference was statistically signifi cant(P<0.05).Conclusion Low molecular weight heparin combined with magnesium sulfate has a signifi cant effect on the treatment of severe preeclampsia,which can improve the blood status and control the blood pressure balance.
作者
韦晓伦
Wei Xiaolun(Department of Obstetrics and Gynecology,Hechi People's Hospital,Hechi 547000,China)
出处
《实用妇科内分泌电子杂志》
2021年第4期16-18,共3页
Electronic Journal of Practical Gynecological Endocrinology
关键词
重度妊娠期高血压疾病
低分子肝素
硫酸镁
Severe pregnancy hypertension syndrome
Low molecular weight heparin
Magnesium sulfate
