摘要
目的针对碳酸氢钠溶液联合派瑞松软膏用于治疗真菌性外耳道炎的临床效果进行观察,并分析其作用机制及优劣性。方法该研究采取回顾性分析的方法,以临床诊治的真菌性外耳道炎患者为观察对象,抽取2015年3月—2020年3月的60例患者资料,按照患者采取治疗方法的不同进行分组,每组30例,采取碳酸氢钠溶液冲洗耳道并用达克宁乳膏涂耳方法治疗的患者归纳为对照组,采取碳酸氢钠溶液冲洗耳道并用联合派瑞松软膏涂耳的患者归纳为观察组,对比观察两组患者治疗前后的炎性因子水平、治疗效果及真菌性外耳道炎的复发率。结果治疗前,两组患者炎性因子水平比较,差异无统计学意义(P>0.05),治疗后,观察组患者炎性因子水平明显低于对照组,差异有统计学意义(P<0.05)。观察组患者治疗有效率为96.67%,对照组患者治疗有效率为83.33%,观察组患者治疗效果优于对照组,差异有统计学意义(χ^(2)=8.989,P=0.029)。观察组患者复发1例(3.33%),对照组患者复发7例(23.33%),观察组复发率明显于对照组,差异有统计学意义(χ^(2)=4.500,P=0.034)。结论碳酸氢钠溶液联合派瑞松软膏治疗真菌性外耳道炎可以提高治疗效果,降低复发率,适合临床推广。
Objective To observe the clinical effect of sodium bicarbonate solution combined with Parvisone ointment in the treatment of fungal otitis externa,and to analyze its mechanism of action and its advantages and disadvantages.Methods This study adopts a retrospective analysis method,taking clinically diagnosed and treated patients with fungal otitis externa as the observation object,extracting the data of 60 patients from March 2015 to March 2020,and grouping them according to the different treatment methods adopted by the patients.There were 30 cases in each group.Among them,the patients who took sodium bicarbonate solution to rinse the ear canal and treated with dakning cream ear method were classified as the control group,and the patients who took sodium bicarbonate solution to rinse the ear canal and applied the combined parison ointment to the ear were summarized as observation group,compare and observe the levels of inflammatory factors before and after treatment,the treatment effect and the recurrence rate of fungal otitis externa.Results Before treatment,there was no statistically significant difference in the levels of inflammatory factors between the two groups of patients(P>0.05).After treatment,the levels of inflammatory factors in the observation group were significantly lower than those in the control group,and the difference was statistically significant(P<0.05).The treatment effective rate of patients in the observation group was 96.67%,and the treatment effective rate of patients in the control group was 83.33%.The treatment effect of patients in the observation group was better than that of the control group,and the difference was statistically significant(χ^(2)=8.989,P=0.029).1 patient in the observation group relapsed(3.33%),7 patients in the control group relapsed(23.33%).The recurrence rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(χ^(2)=4.500,P=0.034).Conclusion Sodium bicarbonate solution combined with P
作者
徐洪
XU Hong(Department of Otorhinolaryngology,Liangxiang Hospital,Fangshan District,Beijing,100000 China)
出处
《世界复合医学》
2021年第4期196-198,共3页
World Journal of Complex Medicine
关键词
碳酸氢钠溶液
派瑞松软膏
真菌性外耳道炎
Sodium bicarbonate solution
Pevisone ointment
Fungal otitis externa
