摘要
2型糖尿病(T2DM)常伴发微血管及大血管病变,但在疾病早期未受到足够重视。因此,需要更多的辅助检测方法对T2DM及高危患者进行早期筛查、辅助诊断。近年来,动脉硬化检测特别是脉搏波速度(PWV)作为一种无创的测量动脉硬度的有效方法,其应用越来越广泛。现有研究表明,动脉硬度增加是T2DM患者血管病变发生发展的重要预测因素。为了更好地在疾病发生前进行预判,以便及早启动健康管理,应用PWV预测动脉硬化显得尤为重要。该文对PWV与T2DM微血管、大血管并发症的相关性进行综述,旨在为早期预判和管理具有血管病变风险的T2DM患者提供参考。
Type 2 diabetes mellitus(T2DM)is often clinically associated with mi-and macrovascular diseases,but is often ignored in the early stage of the disease.Therefore,more auxiliary detection methods are needed clinically for early screening and auxiliary diagnosis of T2DM and high-risk patients.Arteriosclerosis detection--especially pulse wave velocity(PWV),as a noninvasive and effective method for measuring arterial stiffness,has been applied more and more widely in clinic recent years.Existing studies have shown that increased arterial stiffness is an important predictor of the occurrence and development of vascular diseases in T2DM.The value of PWV in the prediction of atherosclerosis is particularly important in order to better predict the occurrence of disease and start health management as soon as possible.Therefore,the relationship between PWV and mi-and macrovasular complications in T2DM is reviewed in present paper to provide early warning for patients with T2DM who have early vascular risk.
作者
李炜祯
王倩
董哲毅
张伟光
陈香美
Li Wei-Zhen;Wang Qian;Dong Zhe-Yi;Zhang Wei-Guang;Chen Xiang-Mei(School of Clinical Medicine,Guangdong Pharmaceutical University,Guangzhou 510006,China;Department of Nephrology,the First Medical Center of Chinese PLA General Hospital/Chinese PLA Institute for Nephrology/State Key Laboratory of Kidney Disease/National Clinical Research Center for Chronic Kidney Disease/Beijing Key Laboratory of Kidney Disease Research,Beijing 100853,China)
出处
《解放军医学杂志》
CAS
CSCD
北大核心
2021年第5期492-497,共6页
Medical Journal of Chinese People's Liberation Army
基金
国家自然科学基金(81700629)
国家重点研发计划(2018YFC1704203)
国家科技重大专项(2019ZX09201-005)
北京市科技计划(D171100002817002)
解放军总医院大数据项目(2019MBD-053)。
关键词
脉搏波速度
糖尿病
2型
动脉硬化
血管并发症
pulse wave velocity
diabetes mellitus,type 2
arteriosclerosis
vascular complications
