摘要
目的探讨富纤维方便米饭对超重/肥胖T2DM患者血糖、血脂和IR的影响及干预机制。方法选取2019年6月至2020年5月常住北京的超重/肥胖T2DM患者53例,随机分为试验组(Tri)28例及对照组(Con)25例。以80 g/d试验米饭替代主食。观察4周后糖化白蛋白(GA)、血脂及IR等指标变化。结果与Con组比较,Tri组GA降低,但差异无统计学意义(P=0.112);TC、LDL-C降低(P=0.008、0.032)。Tri组GA干预后较干预前降低(P=0.008),Con组干预前后差异无统计学意义(P>0.05)。结论富纤维方便米饭可短期改善超重/肥胖T2DM患者血糖和血脂水平且易于接受,但相关机制仍需进一步探究。
Objective To investigate the effects of fiber-rich instant rice on blood glucose,blood lipid and insulin resistance(IR)in overweight/obese patients with type 2 diabetes mellitus(T2 DM)and its intervention mechanism.and randomly divided into two groups:treatment group(Tri,n=28)and control group(Con,n=25).The participants were asked to replace their staple food with 80 g experimental instant rice every day.After4 weeks follow up,glycosylated serum albumin(GA),blood lipid and IR were evaluated.was similar between the two groups(P=0.112).The total cholesterol(TC)and low density lipoprotein cholesterol(LDL-C)both decreased significantly(P=0.008,0.032).GA decreased significantly in the study group compared with baseline(P=0.008),but there was no statistical difference in GA in Con group before and after treatment.levels in overweight/obese type 2 diabetic patients in a short term,and the patients were willing to accept it.But the related mechanism still needs to be explored.
作者
李齐菲
时小东
刘琰
王雪
葛瑞彬
柳嘉
夏凯
陈伟
LI Qifei;SHI Xiaodong;LIU Yan(Department of Clinical Nutrition,Peking Union Medical College Hospital,Beijing 100730,China)
出处
《中国糖尿病杂志》
CAS
CSCD
北大核心
2021年第4期279-283,共5页
Chinese Journal of Diabetes
基金
2019年北京市科学技术委员会“营养健康预警测评平台建设及其指标体系的构建研究”(Z191100008619006)。
关键词
方便米饭
糖化白蛋白
血脂
糖尿病
2型
Instant rice
Glycosylated serum albumin
Blood lipid
Diabetes mellitus
type 2
