摘要
ABO亚型主要表现为抗原凝集强度的减弱、混合视野的凝集反应、抗体效价降低、正反定型不符;其中混合视野的凝集反应是B_(3)亚型最大的血清学特征,通过回顾性分析整理1例疑似B_(3)亚型的血型血清学试验结果、唾液中和试验结果、亲和力试验结果、家系ABO血型调查结果,并结合病史,最终确定先证者及先证者儿子均为B_(3)亚型。因此掌控B_(3)亚型的实验室特征,B_(3)亚型鉴别诊断要点,应用正确试验方法准确鉴定B_(3)亚型,选择合适的血液输注,可以减少输血不良反应的发生。
ABO subtypes are mainly featured by decreased antigen agglutination intensity,agglutination reaction in mixed vision,decreased antibody titer and inconsistent positive and negative typing.Among them,the agglutination reaction in mixed vision is the most important serological feature of B_(3)subtype.Through retrospective analysis and sorting out of the blood group serological test results,saliva neutralization test results,affinity test results and genealogical ABO blood type survey results of a suspected B_(3)subtype,and combining with medical history,it was finally determined that the proband and the proband′s son were both B_(3)subtypes.Therefore,controlling the laboratory features of B_(3)subtype,the key points of differential diagnosis of B_(3)subtype,applying the correct test methods to accurately identify B_(3)subtype,and selecting the appropriate blood transfusion can reduce the incidence of adverse reactions of blood transfusion.
作者
王春海
王文梅
孙然
WANG Chunhai;WANG Wenmei;SUN Ran(Department of Blood Transfusion,Inner Mongolia Baogang Hospital,Baotou014010,China;Intensive Care Unit,the First Affiliated Hospital of Baotou Medical College,Inner Mongolia University of Science and Technology,Baotou014010,China)
出处
《中国现代医生》
2021年第11期147-149,共3页
China Modern Doctor
基金
内蒙古自治区包头市科技计划项目(2018C2007-3-3)。
