摘要
目的调查赣州地区儿童变应性鼻炎的流行病学情况,并分析粉尘螨滴剂治疗的临床效果。方法对2018年1月~2020年1月赣州地区的160例变应性鼻炎患儿进行调查,记录其临床症状与标准变应原皮肤点刺试验(SPT)情况,并观察患儿治疗前后的临床症状积分、临床体征评分变化情况、疗效与不良反应发生情况。结果160例患儿的临床症状主要表现为喷嚏、鼻塞,其他鼻部症状则表现为鼻痒、流涕与嗅觉减退。160例患儿中,SPT阳性患儿共145例,其中5~7岁50例(34.48%),8~10岁63例(43.45%),11~14岁32例(22.07%)。其中,尘螨点刺阳性率最高,占78.62%;其次为玉米花粉、柳树花粉。治疗后,患儿的喷嚏、流涕、鼻塞、鼻痒症状积分与临床体征评分均低于治疗前(P<0.05)。160例患儿中,显效102例(63.75%),有效54例(33.75%),无效4例(2.50%),总有效率为97.50%,而不良反应发生率为5.00%。结论变应性鼻炎患儿的临床症状以喷嚏为主,且患儿皮肤点刺检测多为尘螨过敏,应用舌下含服粉尘螨滴剂治疗有助于改善临床症状与临床体征,且不易发生不良反应。
Objective To investigate the epidemiology of allergic rhinitis in children in Ganzhou area,and to analyze the clinical efficacy of Dermatophagoides Farinae Drops.Methods A total of 160 children with allergic rhinitis were investigated in Ganzhou area from January 2018 to January 2020.The clinical symptoms and the standard allergen skin prick test(SPT)were recorded.The symptoms scores change and clinical sign score changes before and after treatment,curative effect and adverse reactions were observed.Results The mainly clinical symptoms of 160 children were sneezing and nasal congestion.Other nasal symptoms were nasal itching,runny nose and hyposmia.Among 160 children,there were 145 children with SPT positive,50 cases(34.48%)aged 5-7 years,63 cases(43.45%)aged 8-10 years,32 cases(22.07%)aged 11-14 years.Among them,the positive rate of dust mite sting was the highest,accounting for 78.62%,followed by corn pollen and willow pollen.After treatment,the scores of symptoms and clinical signs of sneezing,runny nose,nasal congestion,and nasal itching were lower than those before treatment(P<0.05).Among the 160 children,102 cases were markedly effective(63.75%),54 cases were effective(33.75%),4 cases were ineffective(2.50%),and the total effective rate was 97.50%,the incidence of adverse reactions was 5.00%.Conclusion The mainly clinical symptoms of children with allergic rhinitis are sneezing,and most of the children′s skin prick tests are allergic to dermatophagoides farinae.The application of sublingual Dermatophagoides Farinae Drops can help improve the clinical symptoms and clinical signs,and the adverse reaction rarely occurr.
作者
王心涛
杨明福
高树峰
张克辉
黄振河
蔡云香
黄芸
WANG Xin-tao;YANG Ming-fu;GAO Shu-feng;ZHANG Ke-hui;HUANG Zhen-he;CAI Yun-xiang;HUANG Yun(Department of Otolaryngology,Ganzhou People′s Hospital,Jiangxi Provinmce,Ganzhou341000,China)
出处
《中国当代医药》
CAS
2021年第14期134-137,共4页
China Modern Medicine
基金
江西省卫生健康委科技计划立项课题(20197379)。
关键词
赣州地区
儿童变应性鼻炎
流行病学调查
粉尘螨滴剂
Ganzhou area
Allergic rhinitis in children
Epidemiological investigation
Dermatophagoides Farinae Drops
Clinical efficacy
