摘要
目的文章旨在研究血清胆碱酯酶(cholinesterase,CHE)及总胆汁酸(total bile acids,TBA)两项指标在肝炎肝硬化患者临床治疗中的指导价值。方法选取2019年5月-2020年3月于我院住院治疗的确诊为肝炎肝硬化的患者136例,记为肝炎肝硬化组,其中肝炎肝硬化组患者由于Child-Pugh评分不同,又分为A级、B级和C级;另选取同期健康体检者136例记为对照组。分别对两组患者的CHE及TBA水平进行检测,并进行统计学分析。结果肝炎肝硬化组CHE水平均低于对照组,TBA高于对照组,差异具有统计学意义(P<0.05);肝炎肝硬化组中,A、B、C三级的CHE水平依次递减,TBA水平依次递增,各级间差异具有统计学意义(P<0.05)。结论CHE、TBA水平同肝炎肝硬化间存在联系,且可作为判定肝炎肝硬化分级的依据。
Objective To study the guiding value of CHE and TBA in the clinical treatment of patients with hepatitis and cirrhosis.Methods From May 2019 to March 2020,136 patients diagnosed with hepatitis cirrhosis in our hospital were selected as the hepatitis cirrhosis group,and the hepatitis cirrhosis group was divided into Grade A,B and C due to different Child-Pugh scores;another 136 healthy people were selected as the control group.The levels of CHE and TBA in the two groups were detected and statistically analyzed.Results The level of CHE in hepatitis cirrhosis group was lower than that in the control group,and TBA was higher than that in the control group,the difference was statistically significant(P<0.05);in hepatitis cirrhosis group,the level of CHE in Grade A,Grade B,Grade C decreased in turn,and the level of TBA increased in turn,the difference was statistically significant(P<0.05).Conclusion The levels of CHE and TBA are related to the degree of hepatitis and cirrhosis,and can be used as the basis to judge the degree of hepatitis and cirrhosis.
作者
张海珍
ZHANG Haizhen(Department of Laboratory Medicine,General Aviation Hospital,Beijing 100012,China)
出处
《中国卫生标准管理》
2021年第8期66-69,共4页
China Health Standard Management
关键词
肝炎
肝硬化
血清胆碱酯酶
总胆汁酸
血清白蛋白
分级
hepatitis
cirrhosis
serum cholinesterase
total bile acid
serum albumin
grading
